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《Military Medical Journal of South China》 2007-02
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Experimental Observation of Effect of Injectable Surgical Grade Calcium Sulfate as a Substitute for Bone Graft on Lumbar intervertebral Body fusions in Goats

LI Min, ZHOU Yue, WANG Jian,et al. Department of Orthopaedics, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China  
Objective To compare the effect of injectable surgical grade calcium sulfate plus bone obtained from decompression on lumbar intervertebral body fusion with that of fresh autologous iliac crest bone. Methods The intervertebral discs between L3 and L4 ,and L5 and L6 were removed in 12 adult cross bred goats. One selected randomly from both the intervertebral spaces where the intervertebral discs had been removed received fresh autologous iliac crest bone granules and the other did injectable surgical grade calcium sulfate with 50% fresh autologous bone granules obtained from decompression.The treatments were performed by Robinson's procedure. Radiographic and histological examination were performed 6 and 12 weeks after the surgery.Results The two vertebral bodies,between which the spaces received the calcium sulfate and fresh autologous bone granules, were fused well in all the goats 12 weeks after the surgery.Conclusions Injectable surgical grade calcium sulfate can serve as the substitute for iliac crest autogenous graft.
【CateGory Index】: R681.5
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