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《Military Medical Journal of South China》 2007-04
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Clinical Observation of Curative Effect of PMCT Combined with TACE on Moderate or Advanced Hepatocellular Carcinoma

ZHANG Yan-lin,GAN Lin,HUANG Ying-min,et al.Department of Hepatobiliary Surgery,Chongqing Tumor Research Institute, Chongqing 400030, China  
Objective To evaluate the curative effect of percutaneous microwave coagulation therapy (PMCT) combined with transcatheter arterial chemoembolization (TACE) on moderate or advanced hepatocellular carcinoma. Methods Of 40 patients with moderate or advanced hepatic carcinoma, 18 were treated by PMCT combined with TACE (treatment group) and 22 merely by TACE (control group). The curative effects were compared between both the groups. Results The effective rates in the treatment and control groups were 83.4% and 68.3% respectively. Color ultrasound showed that the reduction rate of blood supply for the tumor in the treatment and control groups were 83.0% and 59.0% respectively. The survival rates of 0.5, 1.0, 1.5, 2.0 years were 50%, 27.3%, 0% and 0% respectively in the control group, and 66.7%, 24.4%, 16.7% and 5.6% respectively in the treatment group. The median survival time in the treatment and control groups was 9.6 and 5.7 months respectively. There were significant differences in 1.5 and 2.0 years survival rate and the median survival time between both the groups (P0.05). The blood level of alpha fetoprotein was significantly lower in the treatment group than that in the control group (P0.05). Conclusion PMCT Combined with TACE can enhance the curative effect on hepatocellular carcinoma.
【Fund】: 重庆市卫生局科研项目(渝卫科教[2001]-01-20072)
【CateGory Index】: R735.7
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