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《Military Medical Journal of South China》 2008-01
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Acanthopanacis Senticosi Polysaccharides Protects against Apoptosis of Hippocampal Neurons Induced by H_2O_2

DIAO Bo,TANG Ying,LI De-zhong,et al.Department of Medical Laboratory,Wuhan General Hospital,Guangzhou Military Command,Wuhan Hubei 430070,China  
Objective To investigate the effect of acanthopanacis senticosi polysaccharides(ASPS)on apoptosis of rat hippocampal neurons.Methods The hippocampal neurons were isolated from SD rats aged less than 3 days and cultured,then induced to apoptosis by H2O2.After treated with ASPS,the changes of cell form were observed,the viability of hippocampal neurons was detected with MTT method and the expressions of Bax and Bcl-2 were detected by immunohistochemical method.ResultsThe cell injury of hippocampal neurons in ASPS-treated group was slighter than that in model group.The viability of hippocampal neurons in ASPS-treated group(0.46)was higher than that in model group(0.36)(P0.01).The hippocampal neurons in ASPS-treated group had higher expression of Bcl-2 and lower expression of Bax.ConclusionASPS enhances the anti-apoptotic capacity of hippocampal neurons in a concentration-dependent manner.
【Fund】: 湖北省自然科学基金项目(2001ABB174)
【CateGory Index】: R285.5
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【Citations】
Chinese Journal Full-text Database 5 Hits
1 LI Yu-li, HU Jing-zi, LIU Hui-min, YU Hong-yu, HE Jin, ZHU Wei-jian (Department of Pathology, Changzheng Hospital, Second Military Medical University,Shanghai 200003,China);The Expression of Bcl-2,Bcl-xL and Bax Protein in Colorectal Carcinomas[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-01
2 Yang Shuliang Wang Yang Chen Ning Harbin University of Commerce(Harbin,150076,China);Study on A canthopanax Senticosus Polysaccharide of the Present Situation and the Progress[J];Heilongjiang Medicine Journal;2006-06
3 REN Yong~* ,ZHONG Zhao-yang ,CHEN Shou-song,et al. *~Department of Pathology,Wuhan General Hospital. Guangzhou command,PLA, Wuhan Hubei 430070, China;Correlativity between Cells Apoptosis and Expressions of p53 and bcl-2 in Patients with Colorectal Adenoma or Adenocarcinoma[J];Military Medical Journal of South China;2005-05
4 WANG Xin-chao,ZHAO Ji-qing,DONG Zhao-jun,et al.Department of Toxicology,Third Military Medical University,Chongqing 400038,China;An experimental study on the effect o f Ca2+in PC12 after hypoxia injury[J];Modern Rehabilitation;2002-15
5 Li Xuxia,Chen Qun,Li Xujing;The correlation between mitochondrial DNA mutations and Alzheimer disease[J];Modern Rehabilitation;2003-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Tian-jin et al (Zhangjiakou Institute of Education,Zhangjiakou,Hebei 075000);Studies on the Extraction and Purification Techniques of Polysaccharides from Acathopanax senticosus[J];Journal of Anhui Agricultural Sciences;2009-17
2 Wang Xun, Han Yongsheng, Han Youngzhu,et al Neurology Institute of Anhui Traditional Chinese Medical College, Hefei 230061;Dystrophin expression in muscle tissues of DMD model-mdx mouse after myoblast transfer therapy[J];Anhui Medical Journal;2009-02
3 LI Xiao-Chun,DAI Min,CHEN Peng(Department of Pharmacy,Anhui College of Traditional Chinese Medicine & Anhui Key Laboratory for Resecarch and Development of Traditional Chinese Medicine,Anhui Hefei 230031,China);Protective Effects of Paeonal Against Hyperlipemia Serum Induced Injury of Rat Aortic Endothelial Cells and Its Influence on Adhesion Reaction of Mononuclear Cells with RAECs[J];Journal of Anhui Traditional Chinese Medical College;2010-01
4 LI Yan-bo1,SUN Jing2,LI Jie2(1.Shandong Provincial Hospital,Shandong University,Shandong Ji'nan 250021,China;2.Shandong University of Traditional Chinese Medicine,Shandong Ji'nan 250355,China);Antiangiogenesis Effect of Reinforcing qi and Nourishing yin Recipe and Its Effects on Expression of Vascular Endothelial Growth Factor and Matrix Metalloproteinase 2 in Tumor Cells[J];Journal of Anhui Traditional Chinese Medical College;2010-02
5 LI Yan1,LI Feng2,WANG Si-wang3,XU Hui1(1.Department of Food and Biology Technology,Bengbu College,Bengbu Anhui 233030;2.Department of Hemotology,Nanjing Military Region Nanjing General Hospital,Nangjing Jiangsu 210002;3.Institute of Material Medical,Pharmacy Department,Fourth Military Medical University,Xi′an Shanxi 710032,China);Study on the apoptosis of erythroleukemia K562 cells induced by Andi injection[J];Journal of Bengbu Medical College;2010-07
6 LI Chang-yu1,AI Jun1,LEI Xiu-juan1,ZHANG Jun2(1.Institute of Wild Economic Animal and Plant of Science,China Academy of Agricultural Sciences,Zuojia,Jilin 132109,China;2.Dunhua Forestry Bureau,Dunhua,Jilin 133401,China);Research Progress on Relationship between Living Area and Drug Composition Content of Acanthopanax senticosus (Rupr. EtMaxim) Harms[J];Northern Horticulture;2009-12
7 Zhao Weichun,Li Li,Shen Guifang,et al Zhejiang Chinese Medical University,Hangzhou(310053),China;Study on the Isolation,Purification and Anti-tumor Activity in vitro of the Polysaccharides Extracted from Clematis Huchouensis Tamura[J];Journal of Zhejiang Chinese Medical University;2011-02
8 WANG Duan-ming~(1,2),YI Zhong~3, HAI-Liqiemu~(1,3), CHEN Jing-bo~(1,3)(1. Xinjiang TECON Animal Husbandry Biotechnology Co. Ltd,Urumqi 830000,China; 2. College of Animal Science, Xinjiang Agriculture University, Urumqi 830052,China;3. Xinjiang Academy of Animal Science, Urumqi 830000 China);The Skin Fibroblasts in Vitro Culture in Bovine[J];Grass-feeding livestock;2005-02
9 WANG Lu,XU Ling,GU Xiang-dong,et al.(Department of Prosthodontics,Affiliated Stomatological Hospital,Chongqing University of Medical Sciences,Chongqing 400015,China);Osteoblastic growth peptide induces actin cytoskeletal reorganization in rat osteoblast-like cells[J];Chongqing Medicine;2007-04
10 TIAN Fu-qi,SUN Hao,PAN Peng,et al.(Department of Urology Surgery,Affiliated Hospital,Jiangsu University,Zhenjiang 212001,China);Isolation and identification of RCSC and study of its apoptosis property[J];Chongqing Medicine;2010-03
China Proceedings of conference Full-text Database 4 Hits
1 LI Hua-tao,REN Xiao-li,ZHANG Rong-rong,LI Xiang,LI De-wen, CHEN Meng,SONG Xian-yi,LIU Yun (Department of Veterinary Surgery,College of Veterinary Medicine, Northeast Agricultural University,Harbin 150030,China);Imbalance of ROS and SOD in paclitaxel induced CHMm cells[A];[C];2010
2 ;Effects of Fuyuan capsule on promoting proliferation and synthesis metabolic Function of Chondrocyte in ivtro[A];[C];2007
3 ZHU Yanqin(Department of Pathology,College of Basic Medical Sciences,Henan College of Traditional Chinese Medicine,Zhengzhou 450008);Detecting apoptosis on the human carcinoma cell line MGC-803 with flow cytometer(FCM)[A];[C];2007
4 ZHU Yanqin Xu Yufang Department of Pathology,College of Basic Medical Sciences,Henan College of Traditional Chinese Medicine,Zhengzhou 450008;The study of Oxymatrine on apoptosis of human carcinoma cell line MGC-803 by flow cytometry[A];[C];2008
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Yu Yongqiang,Shao Hua,Huang Tianhua,Shi Jianan,Li Shuliang, Ma Guoxin,DaiXinzhouQccupational Safety & Health Inslitute,The Ministry of Chemical Industry of PRC,Qingdao 260071 The Medical Clooege of Shantou University, shantou 515063;THE EFFECT OF POTASSIUM DICHROMATE ON THECHROMOSOMES IN HUMAN SPERMATOZOA IN VITRO[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1994-05
2 Cheng Xiu-juan, Li Pei-zhen,Sheng Xiao-hua, Li Bai-jun, Zhu Chun-laiDepartment of Pharmacology, Shenyang College of Pharmacy, Shenyang;ANTITUMOR ACTION AND IMMUNOLOGICAL ACTION OF ACANATHOPANAX SENTICOSUS POLYSACCHARIDES[J];Chinese Journal of Cancer;1984-03
3 Li Ninchuan (Physical Education College,Yangzhou University );Effects of Radix Acanthopanacis on Anti-fatigue in Mice[J];JOURNAL OF ANHUI SPORTS SCIENCE;2000-03
4 REN Zhao-jun~1, GUO Cheng-ji~2, LIU Hong-zhen~2(1.Department of Physical Education, Zaozhuang College, Zaozhuang 277160, Shandong China;2. College of Physical Education, Qufu Normal University, Qufu 273165, Shandong China);Study on Effect of "Compound Antioxidants" on GSH Anti-oxidant System of Skeletal Musclesin Training Rats after Exercise[J];Journal of Beijing University of Physical Education;2005-02
5 ZHANG Man ying,AN Ji hong,LI Chang hui (Dept.of Respiration,The Second Hospita,Jilin University,Changchun 130021 China);Study on apoptosis of Spc-A_1 cell induced by acanthophopanax senticosus[J];Journal of Norman Bethune University of Medical Science;2002-01
6 LI Ling 1,JIANG Hong 2, LI Xue-jun 1, ZHANG Li-ming △, LI Tie-ji 1, YU Guang-yan 1,FAN Hong-xue 3 (1.Department of Occupational Health, School of Public Health, Jilin University, Changchun 130021, China;2.Department of Statistics, School of Public Health, Jilin University, Changchun 130021,China;3.Department of Toxicology, School of Public Health, Jilin University, Changchun 130021,China);Effects of formaldehyde on MDA contents and SOD activities in serum and liver of mice[J];Journal of Jilin University of (Medicine Edition);2004-05
7 CHEN Yue 1, WANG Bao-gui 2, ZHANG Gui-ying 2, YAN Wei-qun 3 (1. Department of Pharmacy Analysis,School of Pharmacy,Jilin University,Changchun 130021,China; 2. Department of Nutrition and Food Hygiene,School of Public Health,Jilin University, Changchun 130021,China; 3. Department of Biochemistry,Institute of Frontier Medical Sciences,Jilin University, Changchun 130021,China);Protective effects of acanthopanax senticosus saponins on mice with irradiation damage induced by X-rays[J];Journal of Jilin University of (Medicine Edition);2005-03
8 YE Lin~1, XING Shen-yang~2, LU Yi~1, SUI Chun-sheng~1, WANG Chun-hua~1, ZHANG Li~△,LI Li~# (1. Department of Environment Hygiene, School of Public Health, Jilin University, Changchun 130021, China;2. Department of General Courses, School of Nursing,Jilin University,Changchun 130021,China);Effects of formaldehyde on lipid peroxidation and antioxidase in mouse brain tissues[J];Journal of Jilin University of (Medicine Edition);2005-04
9 LIU Hong-yan~1, XIE Xiang-lin~ 1* , ZOU Hong-bin~2, LIU Kai~1, LI Ye~1 (1. Department of Pharmacology, School of Pharmacy, Jilin University,Changchun 130021,China; 2. Department of Nephrology,First Hospital, Jilin University,Changchun 130021,China);Effect of Acanthopanax senticosus injection on learning and memory of brain multi-infract rats[J];Journal of Jilin University(Medicine Edition);2006-05
10 LI Zhanhui, LIU Zhenhua Department of Neurology, Zhujiang Hospital, First Military Medicine University, Guangzhou 510282, China;Advances at Parkinson' s disease and apoptosis[J];Chinese Journal of Neuromedicine;2003-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Cheng Xiu-juan, Li Pei-zhen,Sheng Xiao-hua, Li Bai-jun, Zhu Chun-laiDepartment of Pharmacology, Shenyang College of Pharmacy, Shenyang;ANTITUMOR ACTION AND IMMUNOLOGICAL ACTION OF ACANATHOPANAX SENTICOSUS POLYSACCHARIDES[J];Chinese Journal of Cancer;1984-03
2 Wang Kun Ren Zhao Ya Li Wang Dai Shu Zhao Meng Lian Lin Rui Yu Meng Song Niang Gao Yan LüZhi Liang Ya Yun Dept. of Cell Biology, Beijing Institute or Cancer Research;IN VIVO EFFECT OF CHINESE MEDICAL COMPOSITUS AND ADENOSINE 3′5′-cAMP ON EHRLICH ASCITES TUMOR CELLS AND ON THE CHANGES OF THE LEVELS OF cAMP AND 3′5′cAMP—PDE ACTIVITY IN THESE TUMOR CELLS[J];Beijing Medical Journal;1980-02
3 Wei Chuanwan Zeng Heping Wang Xiaojuan Xu Shuyong (Department of Chemistry, South China Normal University, GuangZhou,510631);Research Advancement of Polysaccharides[J];Guangdong Chemical Industry;2004-01
4 Shen Hong(The First Military Medical University,Guangzhou,510515);STUDY ON THE QUANTITATIVE METHOD OF IMMUNOHISTOCHEMISTRY(Ⅲ)[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;1995-01
5 Sheng Jiarong; Zeng Linghui; Zai Chun; Cheng Chaoqu(Chem. Dept. Guangxi Teachers College, Nanning, Guangxi, 530001);THE EXTRACTION, ISOLATION ANDSTRUCTURE ANALYSIS OF POLYSACCHARIDS[J];Journal of Guangxi Teachers College;1999-04
6 MENG Qing-fan,YU Xiao-kun,XU Mu-yun,LI Ming-liang, GAO Zhi-hui,FAN Hao,CHU Yu-zhuo,TENG Li-rong(College of Life Science,Jilin University,Changchun 130012,China);Extraction of Acanthopanacis Senticosi Polysaccharides and Their Antioxidative Effect[J];Journal of Jilin University (Science Edition);2005-05
7 PEI LIN; ZONG YAN-YAN;ZHANG LEI,SUN YA-FENG, ZHANG GUANG-YI(The Research Center of Biochemistry and Molecular Biology,Xuzhou Medical college, Xuzhou 221002);STUDIES ON MECHANISM OF THE INHIBITION OF Ca~(2+)/CaM PKII ACTIVITY INDUCED BY HYPOXIA IN RAT HIPPOCAMPAL SLICES[J];ACTA PHYSIOLOGICA SINICA;1997-01
8 Meng Fanxin et al;Extraction of polysaccharides from Acanthopanax senticosus and determination of polysaccharides content[J];Science and Technology of Food Industry;2005-07
9 qian Nong;et al(Gene Research Unit of Suzhou Medical College);Effect of Five Herbs Extracts in PBL Cultures on Human Interferon Stimulating[J];Suzhou University Journal of Medical Science;1997-01
10 WANG Yuping,ZHU Jiwen,HAN Lingxiao,ZHU Shuping,SONG Haiyan,LIU Yinglin Affiliated Hospital of Chinese People s Armed Police Forces Medical College,Tianjin300162,China;Study on Expression of Bax and Bcl-2 Gene in Trophoblast Cells of Placenta of Postterm Labor[J];Tianjing Medical Journal;2003-09
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