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A STUDY OF THE MECHANISM AND FUNCTIONS OF THE TREATMENT TO SUPERFICIAL LESION PIG MENTATION OF RABBITS WITH CATECHINES

Tang Heping 1 Zhang Jiliang 2 Xiao Rong 2 Wen Haiquan 2 Su Yaping 2 (1 The College of Food Science & Technology, HNAU,Changsha,410128) (2 Dermatological Department of the Second Affiliated Hospital, HNMU, Changsha,410011)  
It was found by experiments of animal pharmacology that catechines could evidently reduce the number of dopa positive melanin cells in the lesion area of rabbits because of reducing the pigmentation of local area.The experiment result showed that catechines reduced the pigmentation mainly by means of regulating the free radical system,protecting SOD activity and suppressing tyrosinase activity so as to suppress LPO formation,to reduce the number of the cells containing tyrosinase and to decrease pigmenlation.
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