A clinical study of paroxetine joint psychotherapy in treating poststroke depression with anxiety
He Yan,Wang Xin,Xiang Souwu,et al.Department of Neurology,the central hospital of railway,Jinan 250001
Objective To study effects of Paroxetine joint psychotherapy in treating poststroke depression with anxiety.Method In this study,a total of 272 patients with acute brain stroke were assessed with SDS、SAS.Of these 272 patients 81 who meet the criteria of depression and anxiety after acute brain stroke / of ICD-10 were recruited.These 81 patients were treated with routine antistroke medication,routine antistroke medication with Paroxetine and routine antistroke medication with Paroxetine joint psychotherapy respectively for 6 weeks.The rating scales such as SSS,HAMD,HAMA,BI and so on were used to evaluate the symptoms improvement and side effects.Results The preoalence rate of poststroke depressive combined with anxiety in acute stroke was 29.78%,the comorbidity was 65.85%.According to the decline of SSS score,HAMD score,HAMA score,and increase of BI score of the patients,significant improvement has been showed in all patients. There were significant difference between trial group I or trial group II and the controlled group(P 0.01),trial group I and trial group II(P 0.05).Conclusion All of the three projects had effects on the patients with Poststroke depression with anxiety,routine antistroke medication with Paroxetine is better,and routine antistroke medication with Paroxetine joint psychotherapy is the best.
【CateGory Index】： R749.1