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《Chinese Journal of Practical Neruous Diseases》 2007-03
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Clinical study of treatments and prognosis on depression and anxiety after stroke

Huang Yuying,Li Shaoqing,Li Guofei,et al.Departmen of Neurology,Longhai hospital,Kaifeng 475003  
Objective To investigate the effects of post-stroke depression and anxiety on ability of daily life and nerve function rehabilitation,to study the therapeutic effects of Paroxetine on depression and anxiety in acute stroke.Methods The data in 282 patients with acute stroke were assessed by SDS and SAS,in which the 90 papatients with depression and anxiety were divided into two groups randomly,one of them were treated with Paroxetine others were not treated;45 patients not depression and anxiety as control group randomly.HAMD,HAMA,SSS,BI were assessed to observe the curative effect after treated with Paroxetine.Results The attack rate of depression combined with anxiety in acute stroke was 68.18%.The difference of grade on reducing of SSS and increasing of BI in not treated group and control group were obviously(P0.01)after six weeks.the grade of SSS,BI in treated group and control group was no significant difference.The difference of HAMD、HAMA、SSS、BI in treated group and no treated group(P0.01).Conclusion Post-stroke depression and anxiety can obvious reduced the ability of daily life and nerve function rehabilitation.The patients' ability of daily life and the degree of neurologic functional rehabilitation all can be increased by applying Paroxetine.
【Key Words】: Stroke Depression Anxiety Paroxetine Prognosis
【CateGory Index】: R749.1
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【Citations】
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1 Bao Xiqing, Wang Gengxin & Liu xianchen et al Shandong Mental Health Center, Ji'nan 250014;Depression and corresponding Psychological Intervention after Stroke[J];Chinese Mental Health Journal;2001-04
【Co-citations】
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1 Yao Suhua,Chen Xiaoqing.Department of Neurology,Shanghai Jiangong Hospital,Shanghai 200083;Medical treatment and psychological treatment on patients with post-stroke depression[J];Henan Journal of Practical Neurons Diseases;2005-04
2 He Yan,Wang Xin,Xiang Souwu,et al.Department of Neurology,the central hospital of railway,Jinan 250001;A clinical study of paroxetine joint psychotherapy in treating poststroke depression with anxiety[J];Chinese Journal of Practical Neruous Diseases;2006-01
3 JU Shu-hong,LIU Ai-ning,CAI Li-qun,et al(Department of Neurology,Liqun Hospital of Putuo District,Shanghai 200333,China);Effect of Early Psychological Intervention on Neurological Function Rehabilitation in Patients with Post-stroke Depression with Anxiety[J];Journal of Clinical Research;2008-12
4 CHEN Hairong The First People's Hospital of Shangqiu City,Shangqiu 476100,China;Influence of Anxiety on Rehabilitation of Stroke Patients[J];Journal of Medical Forum;2007-23
5 ;Effect of Supportive Psychological Care for Past-Stroke Depression Recovery of Neurological Function[J];China Foreign Medical Treatment;2009-17
6 Su Zhanqing , Zhai Yi, Huang Min , et al. (Rehabilitation Department of Brain Hospital, Nanjing Medi-cal University, Nanjing 210029);A Preliminary Clinical Study on Post - stroke Comorbid Anxiety and Depression[J];Nervous Diseases and Mental Hygjene;2002-04
7 He Yan, Wang Xin, Xiao Chunling, et al. (Department of Neurology, the Central Hospital of Railway Station, Ji’nan 250001, China);Prospective Study of Effects of Paroxetine with Mental Intervention on Depression and Anxiety after Stroke[J];Nervous Diseases and Mental Hygjene;2005-01
8 ZHANG Min. Department of Neurology, Chongqing Emergency Center, Chongqing 400014, China;Infarction depression on the rehabilitation of neurological function and its intervention[J];Chinese Journal of Disease Control & Prevention;2007-04
9 Mei Gang,Lu Rong,Ye Qin,et al.Nanjing Medical University Affiliated Brain Hospital 210029,P.R.China;A controlled trial comparing the total rehabilitation of paroxetine and fluoxtine in the treatment of poststroke depression[J];Heath Psychology Journal;2001-06
10 Ni Junzhi. The First Central Hospital of Tianjin. 300011 P.R.China;Reserching of Mixed anxiety and Depressive Disorder[J];Heath Psychology Journal;2005-05
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