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《Chinese Journal of Practical Neruous Diseases》 2007-03
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Clinical study of treatments and prognosis on depression and anxiety after stroke

Huang Yuying,Li Shaoqing,Li Guofei,et al.Departmen of Neurology,Longhai hospital,Kaifeng 475003  
Objective To investigate the effects of post-stroke depression and anxiety on ability of daily life and nerve function rehabilitation,to study the therapeutic effects of Paroxetine on depression and anxiety in acute stroke.Methods The data in 282 patients with acute stroke were assessed by SDS and SAS,in which the 90 papatients with depression and anxiety were divided into two groups randomly,one of them were treated with Paroxetine others were not treated;45 patients not depression and anxiety as control group randomly.HAMD,HAMA,SSS,BI were assessed to observe the curative effect after treated with Paroxetine.Results The attack rate of depression combined with anxiety in acute stroke was 68.18%.The difference of grade on reducing of SSS and increasing of BI in not treated group and control group were obviously(P0.01)after six weeks.the grade of SSS,BI in treated group and control group was no significant difference.The difference of HAMD、HAMA、SSS、BI in treated group and no treated group(P0.01).Conclusion Post-stroke depression and anxiety can obvious reduced the ability of daily life and nerve function rehabilitation.The patients' ability of daily life and the degree of neurologic functional rehabilitation all can be increased by applying Paroxetine.
【CateGory Index】: R749.1
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