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《Bulletin of Hunan Medical University》 2002-04
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Efficacy of erigeron on diabetic peripheral neuropathy

WU Jing, ZHONG Hui ju, SUN Zhi xiang, et al. (Department of Endocrinology, Xiangya Hospital, Central South University, Changsha 410008, China)  
Objective To investigate the efficacy of erigeron on diabetic peripheral neuropathy (DPN), and to obsreve the changes of erythrocyte aldose reductase (AR) activity and serum nitric oxide (NO) level. Methods Sixty four patients with DPN were randomly divided into two groups: erigeron treated group and mecobalamin controlled group. The treatment group received daily erigeron 50 mg, while the control group received daily mecobalamin 500 μg for 3 weeks. The changes of clinical symptoms, sensory nerve conduction velocity (SNCV), AR activity and NO level were observed. Results The AR activity was higher, but the NO level was lower in the diabetic patients before the treatment than those in the healthy controls (P0.01); the AR activity decreased, while the NO level increased significantly after the erigeron treatment, but these parameters had no significant changes after the mecobalamin treatment. The total effective rate and marked effective rate of erigeron in relieving clinical symptoms were significantly higher than those of mecobalamin (85.29% vs 73.33%, 20.59% vs 10.00%, P0.01). Both erigeron and mecobalamin could markedly improve SNCV, but the rising degree of SNCV in the erigeron treated group was higher than that in the mecobalamin controlled group (P0.01). Conclusion Erigeron is able to inhibit erythrocyte AR activity and to increase serum NO level; it can relieve clinical symptoms of diabetic neuropathy, and prompt sensory nerve conduction velocity. The efficacy of erigeron on DPN is better than that of mecobalamin.
【CateGory Index】: R587.2
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Lin Jiayi,Dai Lun,Xu Jiegui (Jiucheng Hospital,Anhui Province,Anhui 246220);Effects of puerar in injection on diabetic peripheral neuropathy[J];Chinese Journal of Diabetes;2000-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Hu Weifen, Jin Jianhong, Wei Yan, et al Hangzhou Municipal Hospital of TCM, Zhejiang Province(310007);Red Sage Injection and Peiduo Puli together Treat Early Diabetic Nephrosis[J];;2006-01
2 Qu Shengying, Chen Xinghua, Yao Ge Affiliated Xin Hua hospital, Shanghai Second Medical University, Shanghai (200092);Study on the Mechanism of Diabetic Peripheral Neuropathy (DPN) Possible Role of Microvascular Damage and Dysfunction[J];Journal of Radioimmunology;2004-03
3 LIU Chunhong. The First Affiliated Hospital of Guangxi College of TCM, Nanning 530023;Therapeutic effect of Hirudo injection on diabetic peripheral neuropathy[J];Hebei Journal of Traditional Chinese Medicine;2002-06
4 ZHU Xu ping, ZHOU Zhi guang (Instirute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011, China);Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy[J];Bulletin of Hunan Medical University;2001-04
5 ;Application of TCM on treating diabetes mellitus peripheral neuropathy[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;2002-11
6 Zhang Zhijing~1,Zhao Jian'an~2 450003No.5 People's Hospital of Zhengzhou,Zhengzhou,Henan,China,450003Saisi Stomatology Hospital,Zhengzhou,Henan,China,450008;A Curative Effect Analysis of Treating Simple Peripheral Facial Paralysis with Dengzhanhuasu Powder and Injection Preparation[J];Journal of Henan University of Chinese Medicine;2006-01
7 ZHANG Mansheng, ZHU Xiaoling, WANG Yongjun Department of Nephrology , Xiaoshan First Affiliated Hospitol of Hangzhou Medical College, Hangzhou (311200);The Effects of Dengzhanhua Injection on Proliferation of Glomerular Mesangial Cells Induced by ET-1[J];Chinese Journal of Integrated Traditional and Western Nephrology;2005-11
8 LI Xiuqin~1 LUO Xinglin~2 ZENG Xiaorong~2 YANG Yan~2(~1Department of Cardiology,the People's Hospital of Weifang,Weifang,261041,China;~2Institute of Cardiovascular Disease,Medicine College of Luzhou);Activation of breviscapine to calcium-activated potassium channels in rat aortic smooth muscle[J];Journal of Clinical Cardiology;2006-06
9 WANG Huan, Wu Guo-de, ZHANG Zhen-chang, SONG Jian-xun, LIANG De-sheng ( Department of Neurology, The Second Hospital of Lanzhou University; Department of Radiology, The Second Hospital of Lanzhou University, Lanzhou, 730030, China);Study on therapeutic effects of breviscapine in the treatment of early hypertensive intracerebral hemorrhage[J];Journal of Lanzhou Medical College;2005-04
10 LIU Lei,SHAO Zhengyi(Department of Pharmacology,Medical College,Nantong University,Nantong 226001);Effects of nerve regeneration factor on peripheral neuropathy of diabetic rats[J];Nantong University Journal of Medical Sciences;2007-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Heng Xianpei,Zhang Farong,Xie Cunguang,Wang Yi (The Affiliated People's Hospital of Fujian TCM College,Fuzhou 350004,China);EXPERIMENTAL RESEARCH OF DIABETIC PERIPHERAL NEUROPATHY TREATED BY TONGLUO TANGTAI[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;2000-02
2 Hong Xingqiu, et al(Institute of Molecular Medicine, Hangzhou 310009);Experimental Study of Pinellia Tuber on Reducing Blood-Lipid[J];Journal of Zhejiang College of Tcm;1995-02
3 Sui Linrong; Hou Fangyu;miao Chunsheng;Liu Jingying;Li Cai(1 Institute of Preclinical Sciences; 2 School of Basic Medical Sciences);Inhibitory effects of some Chinese herb components on nonenzymatic glycosylation in vitro[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1998-06
4 Li Yi ( Department of Ruidong Diabetes Center, Beijing Hospital, Beijing );Effects of Chinese Medicine-TSJN on the Insulin Resistance and Mechanisms by Muscle Fiber Composition in Fructose-Fed Rats[J];China Journal of Traditional Chinese Medicine and Pharmacy;2000-01
5 Zhu Zhangzhi et.al ( The First Affiliated Hospital of Guangzhou University of TCM, Molecular Medicine Center of Zhongshan University);Effect on Rat Insulin Amboceptor of Diabetes 2 of Therapy for Invigorating Qi, Promoting Blood Circulation and Relaxing the Bowels[J];China Journal of Traditional Chinese Medicine and Pharmacy;2002-01
6 Zhang Na et al (Beijing University of TCM);Effect of Cholic Acid and Jasminoidin on Contents of TNF-α, IL-1β and ICAM-1 in Rat Brain with Injury of Cerebral Ischemia and Reperfusion[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-08
7 Pang He~1 Zhu Lingqun~1 Zhang Wensheng~2 Wang Shuoren~1 Niu Fuling~1 Cui Wei~1(()~1 The Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Dong Zhi Men Hospital,Beijing University of Traditional Chinese Medicine,Beijing 100700;()~2 College of Resources Science,Beijing Normal University,Beijing 100875);Effects of Danshensu on Mitochondrion Membrane Potential and Apoptosis during Injury Induced by Hypoxia/Hypoglycemia in Cultured SH-SY5Y Cell[J];China Journal of Traditional Chinese Medicine and Pharmacy;2006-06
8 Ruan Zhipeng,Yu Weidong Department of Pharmacy,Putian University,Putian Fujian;Experimental Study on Anti-inflammation Influence of Scutellarin[J];Journal of Changzhi Medical College;2004-02
9 CHEN Li- li (Shenyang Railway Bureau Shenbei Hospitol, Shenyang 110013, China);Clinical Observation on Effect of Breviscapin in Treating Patients of Coronary Heart Diease[J];Journal of Dalian University;2001-02
10 ZHENG Hong Liang 1, YOU Zhen Dong 2, ZHOU Shui Miao 1, LI Zhao Ji 1, LU Chang Lin 2, YAN Jin 2, WANG Cheng Hai 2, SHAN Jin Jie 1 (1. Department of Otolaryngology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China;Expression of ciliary neurotrophic factor in ambiguous nucleus motoneuron after long-term laryngeal denervation[J];Academic Journal of Second Military Medical University;2000-12
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 JIANG Liang-duo LI Yao-hui Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing 100070,China;Review of internal Chinese Medicine in 2008[J];Global Chinese Medicine;2009-01
2 CHEN Peng,WANG Dian-hua,LEI Wei-ya,SHEN Zhi-qiang(Yunnan Pharmacological Laboratories of Natural Products,Kunming Medical College,Kunming 650031,China);Effects of Scutellarin on Thrombosis and Platelet Aggregation[J];Journal of Kunming Medical College;2006-04
3 LI Li XIN YinbinDepartment of Geriatrics,the No.1 People Hospital of Huainan,Anhui,232007,China;The efficacy of acute exacerbations of pulmonany heart disease by breviscapine[J];Journal of Clinical Pulmonary Medicine;2005-06
4 WANG Yin-hui, LI Hui (Department of Pharmacology, Dali College, Dali China 671000);Effectiveness of Erigeron breviscapus against hepatic fibrosis[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2009-07
5 FENG Juan1,Lü Yan-qing1,LIU Fu-dan1,YAN Qun-chao2,YE Chun-ling1 (1.Department of Parmacology,Pharmacy College;2.Clinical Medicine,Medicine College,Jinan University,Guangzhou 510632,China);The amelioration effects of XiaoKeTongLuo granula on peripheral neuropathy in diabetic rats[J];Journal of Jinan University(Natural Science & Medicine Edition);2009-04
6 ZHOU Sujuan(The Troditional Chinese Hospital of Shijiazhuang,Shijiazhuang 050051);Pharmacody Progress and Clinical Evaluation of Dengzhan Xixin Prepartion[J];Evaluation and Analysis of Drug-Use in Hospitals of China;2006-01
7 LI Hua Medical Team,the 6th Dettachment of General Corp of Public Security and Frontier Guard in Guangdong,Shenzhen 518012;Clinical Observation of Astragalus,Erigeron in Treatment of 46 Patients with Idiopathic Nephrotic Syndrome[J];China Modern Doctor;2008-19
8 Ju Shang,Yang Bohua,Lin Dongyang Dept.of Vascular Surgery,Dongzhimen Hospital,Beijing University of Traditional Chinese Medicine(100700),China;Herbal Treatment in Early Diabetic Atherosclerotic Occlusive Disease[J];Chinese Journal of Surgery of Integrated Traditional and Western Medicine;2007-06
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 Chen Xiaoxia,He Bing (Guangdong College of Pharmacy,Guangzhou,P.R.China 510224);Protective Effects of Breviscapine Against Cerebral Ischemia Reperfusion Injury in Rats[J];ACADEMIC JOURNAL OF GUANGDONG COLLEGE OF PHARMACY;1997-02
2 Xu Guang, Zhang li- Ping, Shen Hui-Fen, Hu Chang-Qi(Department of Biochemistry, School of Basic Medical Sciences, Department of Chemistry of Natural Drugs, School of Pharmacy, Shanghai Medical University, Shanghai);INHIBITION OF PROTEIN KINASE C BY SCUTELLAREIN AND ITS ANALOGUES[J];;1993-03
3 Lu, Bu-Feng; Lu, You-Ming; Huang, Yi-Sen(Department of Biochemistry,Zhenjiang Medical College, Zhenjiang 212001)(Naval Neurobiology Research Centre, Nanjing 210049);Effects of Ca ̄(2+) and Protein Kinase C on Glutamate Accumulation in Rat Hippocampal Slices under Ischemic States[J];;1995-01
4 Fan Huachang, Xuan Yuelin (Central Hospital of Shanghai Putuo District, Shanghai, 200062);Investigation on Clinical Curative Effect of Yunnan Dengzhanhua Injection(Herba Erigerontis) for Cerebral Thrombosis and Its Toxicity and Side-effect on 345 Cases[J];Chinese Traditional Patent Medicine;1993-07
5 Duan Youjin; Wang Shaoying;Ichitomo Miwa;et al(Institute of Basic Medicine of Liaoning Provice,Shenyang 110005);Inhibitory effects of some Chinese herbs on the non-enzymatic glycation of proteins[J];CHINESE JOURNAL OF DIABETES;1998-04
6 Zhang Jiaqing and Zhou Yunping(Department of Endocrinology, Changhai Hospital, Second Military Medical College, Shanghai);Inhibition of Aldose Reductase from Rat Lens by Some Chinese Herbs and Their Components[J];China Journal of Chinese Materia Medica;1989-09
7 .LiZhijian,XuNaigui,HeBailing,etal.KidneyInstitute,SunYat-senUniversityofMedicalSciences,Guangzhou510080;Theeffectofticlopidine、breviscapiniandcrocusuponnephritisinducedbycationicbovineserumalbumin(c┐BSA)inrats[J];CHINESE JOURNAL OF NEPHROLOGY;1996-06
8 LI Shu-mei; LIU Bin; CHEN Hai-fen et al (Department of Cardiology, Second Teaching Hospital, Bethune University of Medical Sciences, Changchun 130041);Effect of Puerarin on Plasma Endothelin,Renin Activity and Angiotensin Ⅱ in Patients with Acute Myocardial Infarction[J];Chinese Journal of Integrated Traditional and Western Medicine;1997-06
9 Sarbottam shrestha,Li Chengyan,Yu Shaozu;A comparative histopatholog study of peri lesion zones of cerebral ischemia and cerebral hemorrhage in Wistar rats[J];SRTOKE AND NERVOUS DISEASES;1999-01
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