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《BULLETIN OF HUNAN MEDICAL UNIVERSITY》 1994-06
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A REESEARCH ON ANTIBACTERIAL MECHANISM OF LITSEA CUBEBA OIL EMULSION

Li Peitao;Zhou Jian;Zha Guozhan;Cheng Wen Department of Clinical Microbiology,Hunan Medical University Xia Zhongdi;Yang Junxiang Department of Microbiology,Hunan Medical University  
he ultrastructural alteration under electron microscope,the incorporation experiment ofisotope labelled precusor were used to study the antibacterial mechanism of Litsea cubeba oilemulsiom in Stapgylococcus aureus,Pseudomonas aeruginosa and Candida albicans.The re-sults exhibited that the cell wall and cell membrane of these microbes were damaged in v ‘3rious degrees,the cytoplasm leaked out,the biosynthesis of DNA,RNA,protein and peptido-glycan of bacteria as well as ergosterol of C.albicans were obviously inhibited.Tl、 eresultsshowed that Litsea cubeba oil acted upon the peptidoglycan of bacteria and mannans chitin aswell as sterol of C.albicans.
【Fund】: 国家自然科学基金
【CateGory Index】: R283.6
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