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《BULLETIN OF HUNAN MEDICAL UNIVERSITY》 1999-01
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Experimental study on induction of apoptosis of leukemic cells by Boswellia carterii Birdw extractive

Qi Zhenhua, Zhang Guoping, Zhu Wenfei, et al (Research Labortory of Hematology, Xiangya Hospital, Hunan Medical University, Changsha 410008)  
The purpose of the study was to investigate the apoptosis of leukemic cells induced by Boswellia Carterii Birdw(BCB). The target leukemia cell line HL60 and bone marrow leukemic cells from 30 acute non lymphocytic leukemic(ANLL) patients (3 M 1 11 M 2a 10 M 3 1 M 4a 5 M 5b ) were studied. Apoptosis was detected by morphological observation, DNA electrophoresis, percentage of DNA fragmentation test and flow cytometric cell cycle analysis. It is concluded that BCB can induce apoptosis in ANLL cells and HL60 cells.
【Key Words】： leukemia non lymphocytic acute Boswellia Carterii Birdw apoptosis
【Fund】： 卫生部科学基金
【CateGory Index】： R733.71
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