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《Journal of Zhengzhou University(Medical Sciences)》 2006-04
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Modified left pulmonary orthotopic allotransplantation in rats

ZHAO Gaofeng,BA Yufeng, DING Zhidan,LI Xiangnan, QI Yu, LI Ang, ZHAO Song, WANG Tieshuan Department of Thoracic Surgery, the First Affiliated Hospital, Zhengzhou University; the Key Laboratory of Clinical Medical Sciences of Universities in Henan Province, Zhengzhou 450052  
Aim: To investigate the modified procedures on left pulmonary orthotopic allotransplantation in rats.Methods:Thirty rats received the left pulmonary orthotopic transplantation with the modified three-oversleeve method of artery, vein and bronchus. The advantages of the modified procedures were compared with the traditional pulmonary transplantation. Results:Rats received modified procedures presented better outcomes such as shorter operation time ((32.5±5.3) min), easy operation, less intraoperative and postoperative mortality (16.7%), better pulmonary function and longer survival ((25±4) d).Conclusion: The modified transplantation procedures have advantages compared with the traditional one and should be recommended in rat experimental pulmonary transplantation.
【Fund】: 河南省高校创新人才培养对象基金资助项目HN20052010
【CateGory Index】: R655.3
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