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The effects of three types of macrophages on hemopoietic stem cell(CFU S) in mice

ZOU Dan,QUAN Hongxun,HU Qunyuan,et al (Henan Medical College for Health Staffs, Zhengzhou 450003,China)  
Objective: To study the effects of peritoneal macrophage (PM),alveolar macrophage (AM) and Kupffer cell on CFU S in mice.Methods: Using technique of colony forming unit spleen and histology,the authers studied the effects of three types of macrophages on CFU S,mitosis index and weight of spleen.Results: KC may stimulate proliferation of CFU S and mitosis of granulocytic,erythrocytic and megakaryocytic system significantly,the weight of spleen was increased too,but both PM and AM have no these action.Conclusion: There are different effects on proliferation and differentiation of CFU S in three types of macrophages.
【Fund】: 河南省卫生厅资助项目
【CateGory Index】: R331
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