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《HENAN MEDICAL RESEARCH》 1996-02
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THE EFFECTS OF GYPENOSIDE ON EXPERIMENTAL HYPERLIPIDEMIA IN RATS

Han Xiaoyan; Wei Hong-bo; Lian Jan-xue et al(Department of pharmacology,Medical College,LouYang 471003)  
After the rats with hyperlipidemia were orally treated with the gypenoside(150mg/kg·d)for 12 weaks the blood levels of TC and TG were significantly decreased,and the con-centration of HDL was greatly increased.The contents of TC in the rats liver and aortic wall werealso significantly decreased.It was also found that the concentration of LPO in serums and liversof the rats with hyperlipidemia was markedly reduced by gypenoside,but the activity of SOD waselevated.From results obtained,it is suggested gypenoside possessed the therapeutic on hyperlipi-demia together with hepaticdernage and atherosclerosis.
【CateGory Index】: R965
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【References】
Chinese Journal Full-text Database 4 Hits
1 Lin Yanjun Li Jiachuan Yangming Li Chunyu (Pharmacy School, Chengdu TCM University, Chengdu, Sichuan 611731);Treating Hyperlipoidemia Using Traditional Chinese Medicine[J];World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica;2008-01
2 MA Ping-bo~1,ZHU Quan-hong~2,HUANG Zhong-wei~1(1.Department of Pharmacy,Nanfang hospital,Southern Medical University,Guangzhou 510515,China;2.Department of TCM,Southern Medical University,Guangzhou 510515);Effects of Gynostemma pentaphyllum on the blood—lipid and hemorheology in hyperlipidemia rabbits[J];The Chinese Journal of Modern Applied Pharmacy;2005-06
3 XU Shi Kai, HE Hong 1, WANG Fu Di 2 (Department of Pharmacology, College of Medicine, Tongji University,Shanghai 200331; 1 Department of Preventive Medicine, Shanghai Second Medical University, Shanghai 200025; 2 Department of Naval Medicine,Sec;Protective effects of gypenoside on cultured bovine aortic endothelial cells against injury induced by oxidatively modified low density lipoprotein[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2002-05
4 LI Man,WANG Xin,LI Xiao-mei,LI Qun-wei.(School of Public Health Taishan Medical University,Taian 271016,China);Overview about the Regulatory Function of Chinese Medicinal Herb on Serum Lipids[J];Medical Recapitulate;2010-12
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Cong Xuezi ( Xuzhou Institute of Medicine, Xuzhou );LOWERING SERUM CHOLESTEROL AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROTIC PLAQUES INDUED BY ALFALFA SAPONINS[J];Chinese Pharmacological Bulletin;1988-05
2 SHI Lin, FAN Pan-sheng, WU Ling, YANG Jiang (Dept.of Phar macology, Sushou Medical College, Suzhou. 215007);Anti—oxidation of Tetramethypyrazine in cholesterol—fed rabbits and increase the content of Prostacyclin I-2 in carotid of rats[J];Pharmacology and Clinics of Chinese Materia Medica;1989-05
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Chao et al (Department of Veterinary Medicine,College of Animal Science,Guizhou University,Guiyang,Guizhou 550025 );Effects of Perilla Seed on Blood Lipid Regulation and Lipid Peroxidation of Coturnix coturnix with Hyperlipidemia[J];Journal of Anhui Agricultural Sciences;2008-21
2 WU Xiao-ming(Department of Pharmacy,The First Affiliated Hospital of Anhui College of Traditional Chinese Medicine,Hefei,Anhui,230031);Effect of ginkgo biloba extract on hyperlipidemia and lipid peroxidation in rats[J];Anhui Medical and Pharmaceutical Journal;2009-05
3 LIU Xiao-mei,FANG Zhao-qin,PAN Zhi-qiang,LU Wen-li,SHU Shi,SONG Li-na(Preclinical Medicine College of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China);Comparison between Syndromes in Hyperlipemia Rats Fed with Two Fat-rich Diets[J];Journal of Anhui Traditional Chinese Medical College;2008-02
4 SUI Da yuan *, HAN Cong cheng,YU Xiao feng,QU Shao chun (Department of Pharmacology, School of Pharmacy, Jilin University, Changchun 130021, China);Effects of Acanthopanax senticosus saponins on blood lipid metabolism and antioxidative activity in experimental hyperlipidemia rats[J];Journal of Jilin University of (Medicine Edition);2004-01
5 ZHANG Jin-sheng1 PENG Bo2(1First Affiliated Hospital of Henna College of TCM,Zhengzhou 450008,China;2 Henna College of TCM,Zhengzhou 450000,China);Effect of Ganlan Jiangzhi capsule on gene expression of liver LDLR and blood fat in rat with hyperlipoidemia[J];China Journal of Traditional Chinese Medicine and Pharmacy;2007-10
6 TANG Shi-ying,HU Gui-cai,LI Ke-ji,et al (Department of Preventive Medicine,Chengde Medical College,Hebei Chengde 067000,China);APPLICATION RESEARCH OF HYPERLIPIDEMIC ANIMAL MODEL OF GOLDEN HAMSTER[J];Journal of Chengde Medical College;2002-03
7 LI Jia-chuan1,YANG Na1,MENG Xian-li1*,ZHANG Yi2 (1.Dept of pharmacology,Chengdu University of Traditional Chinese Medicine,Chendu 610075,China;2.Ethnomedicine institute of Chengdu University of Tcm,Chendu 610075,China);Experimental Study on the Effect of QinHe soft Capsule in decreasing the blood glucose and blood lipid[J];Journal of Chengdu University of Traditional Chinese Medicine;2007-01
8 Li Wengxiong, Qu Lifang, Feng Xuemei, et al Chinese Academy of Sciences,Shanghai Institue of Materia Medica (Shanghai,210075,China);Effect of Chinese Complex Prescriptions to LPO, SOD and Erythrocyte Immunity of Experimental Senile Hyperliopoprotememia[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1997-03
9 Guan Zhangshun, Wu Jun, Yu Zelan,et al. (Chenzhou Medical College, Chenzhou, Hunan 423000);Effects on water extract of lotus leaf to Improve in Human's Blood Lipids Disorder[J];Journal of Chenzhou Medical College;2003-03
10 Huang Xiaodan,Han Jianchun;Study on hydrogenated soybean lecithin action to anti-hyperlipidemia[J];Soybean Science & Technology;2009-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 SHEN Hong-wei et al(College of Biological & Food Engineering,Dalian Polytechnic University,Dalian,Liaoning 116034);Study on the Optimum Extraction Condition of Gypenosides[J];Journal of Anhui Agricultural Sciences;2008-04
2 HOU Hui-li,FU Tong-sheng(College of Animal Medicine,Hunan Agricultural University,Changsha,Hunan,410128,China);Research Advance in the Chemical Ingredients and Pharmacological Effects of Gynostemma pentaphyllum[J];Progress in Veterinary Medicine;2006-S1
3 Feng Dao-rong Wei Bin(The People's Hospital of Guangxi Zhuang Autonomous Region,6 Taoyuan Road,Nanning 530021,China;Ruikang Affiliated Hospital of Guangxi Traditional Chinese Medical University,10 Huadong Road,Nanning 530011,China);Effects of Jianling Decoction on the Blood Lipid and Lipid Peroxidationin in Experimental Hyperlipidemia Rats with Yin Deficiency of Liver and Kidney[J];Guangxi Journal of Traditional Chinese Medicine;2009-04
4 SU Xianhong1,YU Zhong-ping2,HAN Feng-ying2,ZHANG Zhi-hui3 ( 1. Liaoning University of Traditional Chinese Medicine,The Second Affiliated Hospital,Shenyang 110034,China; 2. Shenyang First Pharmaceutical CO. ,Ltd. ,NEPC,Shenyang 110141,China; 3. Technology Development CO. ,Ltd. ,NEPC,Shenyang 110141,China);Protective effect of gypenosides on local cerebral ischemia injury in rats[J];Practical Pharmacy and Clinical Remedies;2010-04
5 LUO Wen-zheng1,ZHANG Qing-zhong2,LV Zhi-ping1(1.Southern Medical University,Guangzhou 510515,Guangdong,China;2.Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong,China);The Application of Gynostemma Pentaphyllum Makino in Fatty Liver Disease Treatment[J];Journal of Liaoning University of Traditional Chinese Medicine;2009-08
6 WANG Junzhi,et al(Hubei Province Key Laboratory of Natural Product Research and Development);Degrading Blood-fat Effect of Saponin from Gynostemma Pentaphyllum in Mice with Hrperlipemia[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2007-01
7 SEN Hong-wei1,XIAO Yan-chun2,CHE Ren-guo1,Chen Jin-zi1,JIN Feng-xie1,YU Hong-shan1(1.School of Food Science & Biotechnology,Dalian Polytechnic University,Dalian 116034; 2.Agricultural Product Quantity Analysis Center, Liaoning Agricultural Vocation-technical College,Yingkou 115009);Extraction and content determination of the total gypenosides in Gynostemma pentaphyllum[J];Food Science and Technology;2008-04
8 ZHOU Jian-hua, ZHANG Xing-ya (College of Life Science, Shandong Normal University, Jinan 250014);New research progress of Gynostemma pentaphyllum and application[J];Food Science and Technology;2010-02
9 WANG Yi-ping,TAN Hua-bing,XU Li,WANG Ji-hong,HU Xiao-lin,ZHU De-wen.The People′s Hospital of Hubei Medical University,Shiyan 442000,China;Study on influencing factor of liver function in rabbit with non-alcoholic fatty liver disease[J];Shanxi Medical Journal;2011-01
10 Department of Public Health,Medical School of Xi’an Jiaotong University (Xi’an 710061) Wang Xiaojuan Gao Xiaoyan Huang Ting et al;Effect of monascus compound on blood lipids regulating function in rats[J];Shaanxi Medical Journal;2007-01
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 FAN Pan-sheng SHI Lin (Dept of Pharmacology,Suzhou Medical College. Suzhou 215007);Main saponins of notoginseng and ginseng ginsenosides decrease the contents of tissue lipofuscin and serum lipid peroxides in the old rats[J];Chinese Journal of Pharmacology and Toxicology;1988-04
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