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《Journal of Hainan Medical College》 2008-04
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Anesthesia of patients with hypertension undergoing abdominal emergency operation

ZHANG Cheng-ju,MA Bao-xin,LI Hong-yue(Department of Anesthesiology,Zhongshan Hospital Affilated to Xiamen University Xiamen 361004,China)  
Objective:To investigate the clinical effect and safety of combined application of urapidil and nitroglycerin in generally anesthetized abdominal emergency operation for patients with ASA2~3 hypertension.Methods:Twenty-five ASA2~3 hypertension patients were studred.Before induction and intubation of anesthesia and extubation,urapidil was injected intravenously and then the changes of systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR) were observed from the start till 20 minutes after injection.During the operation,these changes were also observed from the start of intravenous injection of nitroglycerin till 60 minutes and till 30 minutes after injection of nitroglycerin.Results:After intravenous injection of urapidil before induction and intubation of anesthesia,SBP and DBP decreased from 2 till 20 minutes significantly.During the period,no significant change was found in HR.During operation and the course of continuous intravenous injection of nitroglycerin,SBP and DBP but not HR decreased significantly from the start till 30 minutes.Conclusion:Combined application of urapidil and nitroglycerin can effectively control the blood pressure,maintain HR stability during induction and intubation of anesthesia and extubation,and keep stable haemodynamics during the operation.
【CateGory Index】: R614.21
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