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《Journal of Hainan Medical University》 2011-02
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Effect of atomization inhalation of Ambroxol in treating children with Mycoplasmal Pneumonia

ZHOU Guo-dong1,ZHOU Hong2(1.Hospital of Traditional Chinese Medicine in Xianning City,Xianning 437100;2.The Second Hospital Affiliated to Xianning University,Xianning 437100,China)  
Objective: To observe the augmentation effect and safety of atomization inhalation of Ambroxol in treating children with Mycoplasmal Pneumonia.Methods: All 100 children with mycoplasmal pneumonia were randomly assigned to study group(treated with azithromycin combined with ambroxol for 7-14 days) and control group(treated with azithromycin alone for 7-14 days) by half.The clinical efficacy,symptoms disappearing time,treatment time and adverse effect in two groups were observed and compared.Results: In the first weekend after treatment,the clinical efficacy in the study group was significantly higher than those in the control group(χ2=7.95,12.19,5.32,all P0.05),the symptom scores in the study group were lower significantly(t=3.47,P0.05).But in the second weekend,the clinical efficacy and the scores had no significant difference between the two groups(χ2=0.85、0.44、0.00,t=0.68,allP0.05).So was the incidence of adverse effect(χ2=0.30,P0.05).The time of symptoms disappearing and treatment in the study group were significantly shorter.Conclusions: Atomization inhalation of Ambroxol has a good augmentation effect on azithromycin in treating children with mycoplasmal pneumonia.It is safe,and can quickly relieve symptoms and shorten the treatment time.
【Fund】: 海南医学院科研基金资助学报项目(0020110039)~~
【CateGory Index】: R725.6
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