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《Journal of Clinical Research》 2007-06
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The Clinic Application Value of the ADA Determination on Liver Disease Patients

PENG Jian-qiao,CAO You-de(Hunan Provincial People's Hospital,Changsha,Hunan 410005,China)  
【Objective】To investigate the change and value of adenosine deaminase(ADA) on various liver disease patients.【Methods】ADA and alanine aminotransferase(ALT) in serum of various liver disease patients and healthy control were measured and compared with colorimetric method of enzymatic couple.【Results】Both the ADA and ALT of various liver disease patients increased significantly,compared with those of the control patients.As to the liver cirrhosis group,the ADA increased more distinctly than the ALT.The ADAs of the patients with acute hepatitis,chronic active hepatitis and liver cirrhosis were evidently higher than those of the healthy control(P0.01);while the ADAs of the patients with chronic persistent hepatitis and liver cancer were slightly higher than those of the healthy control,and there was no statistic difference.【Conclusion】The ADA measuration has relatively high sensitivity on liver disease diagnoses,and has important clinic values on liver disease differential diagnoses.
【CateGory Index】: R446.1
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【References】
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【Co-citations】
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1 LI Qing-lin,YE Yue-hong,TANG Bo(Department of Clinical Laboratory,Second College of Clinical Medicine,Chongqing University of Medical Sciences,Chongqing 400010,China);Diagnostic value of multiple combined detection indexes in liver diseases[J];Chongqing Medicine;2007-10
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【Secondary References】
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