The Effect of Desmodium Pulchellum on the Content of Liver Collagen Protein of Testing Hepatic Fibrosis Rats
Yu Shengmin, Zhong Ming, Huang Linyun et al (Guangxi Institute of National Medicine, Nanning Guangxi 530001)
Objectives:To investigate the effect of desmodium pulchellum on the content of liver collagen protein of hepatic fibrosis rats induced by CCL4. Methods:Give medicine by ig,Which is equal to crude drugs 5g/kg, or 3g/kg with desmodium pulchellum's water soluble extractive and alcoholic soluble extrative . Results:After eight weeks' successive treating, the content of liver collagen protein of treating groups is obvious less than that of pattern group,liver histopathological examination also confirms that the liver degeneration and necrosis of every treating group, postive group and gap group are not obvious. Conclusions:Desmodium pulchellum has the effect on antihepatic fibrosis. The mechanism is possibly concerned that it can make liver cell immune against injure and deduce indirectly the forming of liver collagen protein.