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《Journal of Practical Diagnosis and Therapy》 2007-12
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Effect of the specific antigen immunotherapy in allergic rhinitis treatment

ZHOU Jiaqing,ZHAO Jiyu.Department of Otolaryngology,Head and Neck Surgery,Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200001,China  
Objective To discuss the efficacy and safety of specific immunotherapy in allergic rhinitis treatment.Methods Eighty-seven patients diagnosed as perennial allergic rhinitis by typical clinical symptom,sign,skin prick test and measurement of dermatophagoides farinae-specific IgE and ECP were given subcutaneous injection with dermatophagoides farinae once a week.Then the changes of symptom and sign were observed to evaluate the therapeutic effect of immuotherapy.Meanwhile,the adverse reaction of immunotherapy was observed.Results The total effective rate of immunotherapy of dermatophagoides farinae injection was 90.8%,the markedly effective rate was 67.81%(the symptom disappearance rate was 55.17%),the ineffective rate was 9.19%.No serious adverse reaction was reported.Conclusion The efficacy and safety of immunotherapy with dermatophagoides farinae injection are satisfying as long as with the correct administration and indication control.
【CateGory Index】: R765.21
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