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《China Journal of Chinese Medicine》 2011-09
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Experiencal Study of Shuangjinlian Heji Antiviral of Lung Infection

Guo Zhong-hua,Liu Wei-wei,Xing Ze-tian Henan Taloph Pharmaceutical Stock,Zhengzhou,Henan,China 450001  
Objective:respectively,through Shuangjinlian Heji on FM1 virus,,inhibition test to investigate the antiviral activity of Shuangjinlian Heji.Methods:Mice gavage,lung index and lung index in mice inhibition test for determination of death in mice infected with the virus protection test the drug were observed at different doses in mice infected with FM1 virus protection.Results:The index of the drug than the dose in lung virus control group was significantly lower(P0.01),lung virus titers than the virus activity were decreased from 1000 to 490 times.Large,medium-dose group,the average survival time with the virus control group was significantly extended(P0.05).CoxB3 have a direct killing effect,but can not inhibit CoxB3 in the cell reproduction.Conclusion:The drug can reduce the lung lesions in mice infected with the virus,Can be applied to influenza virus,lung infection caused by viral colds.
【Fund】: 国家发改委高技术产业化基金项目(编号:豫郑市高工[2008]00093);; 国家重点新产品项目(编号:2010GRD00021)
【CateGory Index】: R285.5
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