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《Henan Traditional Chinese Medicine》 2008-10
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Study on Protective Effect of Modified Sijunzi Decoction and Ginseng Decocted Extract on Exhausted Postkinetic Myocardium of Rats

Zhang Wenguang, Song Danyun, Zheng Minlin(Fujian Colllege of Traditional Chinese Medicine, Fuzhou, Fujian, 350003)  
Objective: To observe the protective action of Modified Sijunzi Decoction and Ginseng dococted extract on rats' myocardium after strength-exhausting activity. Method: The model rats were established with exhausting action. Rats in group A were givern no training exercise and fed regularly with free diet; Rats in group B were strength-exhausted; Rats in group C were fed with Modified Sijunzi docoction after strength-exhausting activity; And rats in group D were fed with Ginseng decocted extract after strength-exhausting activity. After 5 weeks of experiment, the myocardial tissues were taken to observe the myocardial structure, localization and organelle of A,B,C,D groups with type Hu-12A electron miroscope of 75 kv, and to compare their differences. Results: Strength-exhausting activity can lead to the myofilament dissolution of most myocardial cells, the swelling of multitude of mitochondria, and the incomplete sarolemma in some local parts, thus resulting in the overflowing of organelle such as the mitochondrin of myocardial cell. And the myocardial fiber structure and organelle perfused with Modified Sijunzi Decoction and Ginseng decocted extract didn't show obvious change compared with regularly-fed group. Conclusion: Modified Sijunzi Decoction and Ginseng decocted extract have protective action on the myocardia of strength-exhausted rats.
【Fund】: 福建省自然科学基金项目(编号:Z0516043)
【CateGory Index】: R285.5
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