Influence of Daihuang Zhechong Pellet on Immunologic Function of Fxpriental Endometriosis Rats
Zhao Fang1, Chu Yuxia2, Feng Yinman3(1. Institute of Reproductive Medicine, Luoyang Heath Care Center of Maternity and Children, Luoyang, Hennan, 471000;2. Department of Gynecology and Obstetrics, Henan Hospital of TCM, Zhengzhou, Henan, 450002;3. Zhengzhou Board of Health, Zhengzhou, Henan, 450003)
Objective: To observe the influence of Daihuang Zhechong Pellet on EMT immunologic function of rats. Methods: The model rats with endometriosis were randomly divided, according to the volume of ectopic intima, into Duhuang Zhechong Pellet high dose group, Daihuang Zhechong Pellet medium dose group, Western medicine group and Model group. Their indexes were examined after four weeks' treatment of stomach perfusion. Results: Daihuang Zhechong Pellet high dose group, Daihuang Zhechong Pellet mudium dose group and Western medicine group have distinct inhibition to endometriosis. Compared with endometriosis before the treatment, the volume of ectopic intima shrinked distinctly (P0.01), declined serumtumor necrosin-α (TNF-α) level (P0.01); the histopathology analysis showed that Daihuang Zhechong pellet medium can increase distinctly the thickness of thymic cortex, the size of splenic lymph nodules and the number of llymphoeyte, and can lower the density of lymphoeyte of the ectopic intima's gland, lower the density of germinal center (P0.01). Conclusion: The partial mechanism of treating endometriosis by Daihuang Zhechong Pellet may be related with the immunologic function of improving endometriosis rats.
【CateGory Index】： R285.5