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《Global Traditional Chinese Medicine》 2010-04
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Clinical study on Tianle-capsule regulating ET and NO in blood plasma in the patient of migraine

XU Yan-lai,LI Fu-yu,YANG Ming-hui,et al. TCM Department,Qingdao First sanitarium of PLA Jinan Military Unit,Qingdao 266071,China  
Objective To reveal the mechanism of traditional Chinese drug Tianle capsule in treatment of migraine. Methods According to related diagnostic criteria,106 migraine patients,who were divided into two groups,were studied. Among them,54 patients were in treatment group and 52 ones were in control group. Patients in treatment group were administered Tianle capsule for 4 months. And patients in control group were administered Zhengtian pilulae. Then observe the changes of ET and NO in blood plasma. Results The ET in treatment group have more significant differences than those in control group (P0.05). The NO in treatment group have also more significant differences than those in control group (P0.05). Conclusion Tianle capsule can effectively control migraine by ways of decreasing the level of ET,raising the level of NO,regulating vasomotor function,relieving vasospasm and ameliorating cerebral blood flow and etc.
【Fund】: 青岛市科技发展计划项目(2007Z053)
【CateGory Index】: R277.7
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