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《Journal of Infrared and Millimeter Waves》 2010-02
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APPLICATION OF DYNAMIC SPECTRUM AND PARTIAL LEAST-SQUARES IN NONINVASIVE MEASUREMENT OF HUMAN ERYTHROCYTE CONTENT

JIA Ping1,ZHANG Bao-Ju1,ZHANG Zhi-Yong2,3,LIN Ling2,MEN Jian-Long2,4,LI Gang2(1.College of Physics & Electronic Information,Tianjin Normal University,Tianjin 300387,China;2.Tianjin Key Laboratory of Biomedical Detection & Instruments,Tianjin University,Tianjin 300072,China;3.Department of Electromechanical Engineering,Tianjin Agricultural College,Tianjin 300384,China;4.Clinical Laboratory Devision General Hospital of Tianjin Medical University,Tianjin 300052,China)  
Dynamic spectrum (DS) method was used to measure non-invasively human erythrocyte content for the first time.In vivo measurements were carried out to 28 healthy volunteers,and parital least-squares(PLS) regression was used to establish the calibration model of subjects’ erythrocyte content values against DS data.The correlation coefficients were 0.9193 and 0.9058 for calibration set and validation set,respectively.The biggest relative error of validation is 7.96%,and the average relative error is 6.21%.Measurement results show that the influences of individual differences on spectra can be decreased effectively by DS method.This method can measure accurately human erythrocyte content and it is a promising method for non-invasive blood analysis.
【Fund】: 国家自然科学基金资助项目(No.60174032 60674111)
【CateGory Index】: R446.1
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