Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《West China Journal of Stomatology》 2008-04
Add to Favorite Get Latest Update

The effect of basic fibroblast growth factor on the gene expression of decorin by periodontal ligament fibroblasts in culture

WANG Si-cong1, LIN Chong-tao1, NIE Dai-bang2, OUYANG Hong-sheng2. (1. Dept. of Periodontology, Stomatology Hospital of Jilin University, Changchun 130041, China; 2. Dept. of Animal Biotechnology, School of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China)  
Objective To study the effect of basic fibroblast growth factor(bFGF) on the gene expression of decorin by periodontal ligament fibroblasts(PLFs) in culture,and discuss the effect of bFGF in periodontal regeneration. Methods Human PLFs were cultured and stimulated by exogenous bFGF. Gene expression of decorin was assessed by semi-quantitive RT-PCR. Results The mRNA expression of decorin was suppressed by bFGF and the effect was dose-dependent. When the dose of bFGF increased, the inhibitive effect decreased. Conclusion Decorin has many biological effects. The inhibitive effect may be one of important factors which participate in the healing process of periodontitis, and provide partly theoretical basis of bFGF in periodontal regeneration.
【Fund】: 吉林省科技发展计划基金资助项目(200705342)
【CateGory Index】: R78
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 TU Xiao li (Department of Stomotology,NanFang Hospital,First Military Medical University,Guangzhou 510515,China);Growth factors and periodontal tissue engineering[J];Foreign Medical Sciences Biomedical Engineering;2002-02
2 TAN Zhen, GONG Ping,ZHAO Qing.(Key. Laboratory of Oral Biomedical Engineering Ministry of Education, Sichuan University, Chengdu 610041,China);Influence of Basic Fibroblast Growth Factors on the Migration, Proliferation of Osteoblasts and Periodontal Ligament Fibroblasts[J];West China Journal of Stomatology;2005-03
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 CHEN Fang, XU Yan.(Dept. of Periodontology, The Affiliated Hospital of Stomatology, Anhui Medical University, Hefei 230032, China);The progress research of periodontal ligament stem cells[J];International Journal of Stomatology;2008-06
2 SHU Dan, YANG Si-wei. (Dept. of Orthodontics, The Affiliated Hospital of Stomatology, Luzhou Medical College, Luzhou 646000, China);Effects of platelet-derived growth factor-BB and basic fibroblast growth factor on the proliferation of human periodontal ligament cells[J];International Journal of Stomatology;2009-06
3 CHEN Ying,LIN Chong-tao,GAO Ying.(Dept. of Periodontology,Stomatology Hospital of Jilin University,Changchun 130041,China);Effect of basic fibroblast growth factor on the gene expression of epidermal growth factor receptor by periodontal ligament cells in culture[J];West China Journal of Stomatology;2009-03
4 WANG Wen-sheng, CHEN Wen-ming, BAO Gang. Stomatological Section Dongguan Frontier Port Hospital, Dongguan 523071;Analysis on Prognosis and Relative Factors of Intended Tooth Replantation in Treating Refractory and Chronic Periapical Periodontitis[J];Journal of Oral Science Research;2007-02
5 NIE Rui WU Yun-xia (The First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China);The Influence of PDGF-BB and bFGF on the Proliferation of Periodontal Ligament Cell in vitro[J];Journal of Practical Medical Techniques;2007-34
6 LI Zhongming, RUAN Zhixiong, FAN Jiadong, LU Yinkai (Daojiao Hospital of Dongguan City Guangdong Province, Dongguan 523176, China);Clinical analysis of guided tissue regeneration for the treatment of 98 cases with periapical lesions[J];China Modern Medicine;2009-11
7 CHEN Xi,ZHANG Jie.(Department of Stomatology,Kunming Medical College,Kunming 650031,China);Effect of Basic Fibroblast Growth Factor on Periodontal Ligament Fibroblasts[J];Medical Recapitulate;2009-23
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHENG Lei WANG Qian WEI Kuan-hai Pei Guo-xian (Department of Orthopedics and Traumatology. Clinical Laboratory Nanfang Hospital, First Military Medical University. Guangzhou 510515. China);Biological effects of basic fibroblast growth factor on bone marrow stromal cells[J];JOURNAL OF FIRST MILITARY MEDICAL UNIVERSITY;2000-02
2 GE Shao-hua, YANG Pi-shan (Hospital of Stomatology, Shandong Medical University, Jinan 250012,China);The effects of fibronectin on biological characteristics of gingival and periodontal ligament fibroblasts[J];Chinese Journal of Conservative Dentistry;2001-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved