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《Chemical Reagents》 2005-08
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The synthesis and structure of organotin chlorides containing silicon

LIN Sen~*1,2,DENG Rui-hong~2,LU Zhi-qiang~2,YAO Hua~2,SUN Xiao-qiang~1,WANG Xin~1 (1.School of Chemical Engineering,Nanjing University of Science and Technology,Nanjing 210094,China;2.Department of Chemistry,Nanchang University,Nanchang 330047,China)  
Eight organotin chlorides containing silicon were synthesized by the reaction of(RMe_2SiCH_2)_4Sn with SnCl_4,and characterized by ~1HNMR and elemental analysis.The progress of the reactions were monitored with HPLC.Preliminary bioassay tests showed that (RMe_2SiCH_2)_2SnCl_2 had a good antitumour activity in vitro against SPC-A-1 tumour cells.
【Fund】: 江西省自然科学基金资助课题(0020028)。
【CateGory Index】: O614.432
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