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《Chemical Reagents》 2008-12
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Synthesis and structure of butyl(trimethylsilylmethyl)tin arylcarboxylates

LIN Sen1,JIANG Yu-chun1,HE Xiao-li1,ZHENG Jian-xia1,HE Min2,YAO Kai1 (1.Department of Chemistry,Nanchang University,Nanchang 330031,China;2.Department of Zoology,Jiangxi Vocational College of Biological Science and Technology,Nanchang 330200,China)  
Nine butyl(trimethylsilylmethyl)tin arylcarboxylates were synthesized by the reaction of butyl(trimethylsilylmethyl)tin dihalides with arylcarboxylic acids in the presence of triethyl amine,and their structures were characterized by IR,1HNMR and 13CNMR spectra.The preliminary bioassay tests showed that the compound Bu(Me3SiCH2)Sn(OCOC6H4NO2-p)2 exhibited a good antitumour activity in vitro against lung tumour cells A549.
【Fund】: 国家自然科学基金资助项目(20762006);; 江西省自然科学基金资助项目(0520064)
【CateGory Index】: O627.42
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