Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chemistry》 2010-06
Add to Favorite Get Latest Update

Progress of β-Elemene and its Derivatives

Zhang Shujia,Zhou Peng,Duan Huaxin,Yuan Han(Key Laboratory of Bioorganic Chemistry of Liaoning Province,College of Environment Science and Chemical Engineering,Dalian University,Dalian 116622)  
β-Elemene is a novel anticancer drug,which was extracted from the ginger plant and has been applied in clinics.β-Elemene exhibits excellent anti-tumor properties,it has attracted more interest.However,it is necessary to improve by structural modification due to its shortcoming such as low activity,less water-soluble etc.The syntheses about the derivatives of β-Elemene containing halogeno-,nitrogen-,esters,glycosides and so on,combined the authors'work,are reviewed.The modifications of β-Elemene are emphatically introduced.
【Fund】: 国家自然科学基金项目(30873143);; 辽宁省高校创新团队项目(2008T005)资助
【CateGory Index】: TQ463.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 9 Hits
1 Gong Guoliang, Cheng Guobao, Hu Jiehan, Cheng Yuesheng, Dai Jianying (Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023);STUDY ON THE CATALYTIC HYDROGENATION OF β ELEMENE BY PALLADIUM AND RHODIUM[J];CHINESE JOURNAL OF CATALYSIS;1999-01
2 Zou Lijuan,Li Jie,YuLimin,et alDepartment of Oncolgy,Second Hospital of Dalian Medical University;The antitumor activity of β-elemene associated with apoptosis[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;1998-02
3 YANG Lan-Yi1,ZHANG Shu-Jia1,2,ZHENG Xue-Fang2,YIN Hong-Xing1(1.College of Environmental and Chemical Engineering,Dalian University,2.Key Laboratory of Bioorganic Chemistry of Liaoning Province,Dalian 116622,China);Design and Synthesis of β-Elemene Glycoside Derivatives Containing Heteratom S or Se[J];Chemical Journal of Chinese Universities;2008-11
4 Lu Bufeng, Yu Limin, Bian Chunxiang, Shao Shujuan, Zhu Zhengmei, Yang Peiman (Key Laboratory of Cellular and Molecular Biology of Liaoning Province, Dalian Medical University, Dalian 116027,China);EXPERIMENTAL STUDIES ON ANTI CANCER FUNCTION OF PIC-BE[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;2000-01
5 Sun Hong (Normal college of Shenyang University,Shenyang 110015,China)\;Lian Xiaohong\;(Dalian Institute of Medical and Pharmaceutical Science, Dalian 116013,China);Study about the Stability of β-Elemene and γ-Elemene[J];SHENYANG CHEMICAL INDUSTRY;1999-03
6 YIN, Hong-Xinga ZHANG, Shu-Jiaa,b ZHENG, Xue-Fang*,b YANG, Lan-Yia (a College of Environment and Chemical Engineering, Dalian University, Dalian 116622) (b Liaoning Key Laboratory of Bioorganic Chemistry, Dalian University, Dalian 116622);One-Pot Synthesis of β-Elemene-13-yl Alkyl Selenides[J];Chinese Journal of Organic Chemistry;2008-08
7 YANG, Lan-Yia ZHANG, Shu-Jiaa,b ZHENG, Xue-Fang*,b YIN, Hong-Xinga (a College of Environmental and Chemical Engineering, Dalian University, Dalian 116622) (b Key Laboratory of Bioorganic Chemistry of Liaoning Province, Dalian 116622);Synthesis of β-Elemene Glycoside Derivatives[J];Chinese Journal of Organic Chemistry;2008-10
8 CHENG Kang-Min, SHEN Yu-Mei, WANG Mou-Hua, FENG Cui-Lan(Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800);Synthesis of β-Elemene Amino Acid Derivatives[J];Chinese Journal of Applied Chemistry;2008-05
9 ZHANG Xing-zhong1,XU Li-ying1,TAO Shu-juan1,WANG Xian-ming2,CHEN Guang2,WANG Min-wei2,DONG Jin-hua1(1.School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang 110016,China;2.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);Synthesis and antitumor activity of β-elemene-13-yl esters[J];Chinese Journal of Medicinal Chemistry;2007-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HUANG Jun et al (Guangxi Traditional Chinese Medicine University,Nanning,Guangxi 530001);Chromosome Karyotype Analysis of Curcuma kwangsiensis[J];Journal of Anhui Agricultural Sciences;2010-28
2 WEI Hui-ping et al(Panzihua University,Panzihua,Sichuan 617000);Separation of β-elemene from Eupatorium adenophorum by Macroporous Resin Column Chromatography[J];Journal of Anhui Agricultural Sciences;2012-22
3 LIANG Guang,LI Xiao-kun,LIU Min,HUANG Zhi-feng (School of Pharmacy,Wenzhou Medical College,Wenzhou Zhejiang 325035);Progress on pharmacological properties of zedoary turmeric oil[J];Anhui Medical and Pharmaceutical Journal;2006-12
4 TAN Guang1, WANG Zhong-Yu1, WANG Xiao-Gang2, CHENG Lei1, YIN Shuo1 1. Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, 116011, P. R. China 2. Department of General Surgery, Pucheng PeopleFs Hospital, Pucheng, Shaanxi, 715500, P. R. China;Immunotherapeutic Effects of β-elemene Combined with Interleukin-23 Gene-modified Dendritic Cells on Murine Pancreatic Carcinoma[J];Chinese Journal of Cancer;2006-09
5 WANG Zhi-hong1,XUE Jian-bin2,JIANG Wen-yan2,ZHANG Gui-rong2(1.Basic Medical College,Changchun University of Chinese Medicine,Changchun 130117,China; 2.Life Science College,Jilin University,Changchun 130012,China);A study on effects of Menispermum dauricum alkali polysaccharide on Hela cell proliferation[J];Journal of Northeast Normal University(Natural Science Edition);2011-04
6 Liu Hui-jun~1,Cui You~2,Zhou Chong~1,et al. (1 School of Pharmacy,Yantai University,Yantai 264005;2 Zhejiang Tianrui Pharmaceutical Co.,Ltd,Ruian 325200,China);Discussion About the Content Determinationof Essential Oil of Curcuma Wenyujin[J];Chinese Journal of Medicinal Guide;2009-11
7 DOU Yu-qin1, LIU Yu-xin1, YAN Hui-fang2, LU Hong-qi2 (1. Dalian Institute of Medical and Pharmaceutical Sciences, Dalian 116013, China; 2. Laboratory of Pharmacology, Shanghai Institute of Pharmaceutical Industry,Shanghai 200437, China);Anti-tumour activity of concentrated elemene injection in vitro[J];Journal of Dalian Medical University;2005-06
8 GONG Hai-ming1,ZHAO Hua2(1 College of Life Science and Technology,Gansu Agricultural University,Lanzhou 730070;2 Shaanxi University of Technology,Bio-Resources Key Laboratory of Shaanxi Province,Hanzhong,Shaanxi 723001,China);Analysis of Volatile Constituents in Evodia rutaecarpa Benth.from Various Habitats and Evodia lenticellata Huang by GC-MS[J];Acta Botanica Boreali-Occidentalia Sinica;2008-03
9 RAN Ping, LIU Bin (Children's Hospital, Chongqing Medical University, Chongqing 400014, China);Application of zedoary turmeric oil and glucose injection to child patients[J];Journal of Pediatric Pharmacy;2005-01
10 Wang Yu1,2,Sun Chang-hai1,Xu Ming-liang1,Fang Hong-zhuang1,Li Shou-jun1(1.Chemical and Medical College of Jiamusi University,Jiamusi,Heilongjiang 154007,China;2.Harbin Pharmaceutical Group Co.,ltd,General Pharm.Factory,Harbin 150086,China);Identification of Curcuma longa and other 3 Chinese Traditional Drug by Oscillating Fingerprint[J];Fujian Analysis & Testing;2010-02
China Proceedings of conference Full-text Database 5 Hits
1 ZHOU Chong~1 Liu Hui-jun~1 Cui You~2 SUN Xiu-yan~1 (1.School of Pharmacy,Yantai University,Yantai 264005,China; 2.Zhejiang Tianrui Pharmaceutical Company Limited,Ruian 325200,China);Separation and Identification of Curzerene in Curcuma Wenyujin Oil[A];[C];2011
2 Liu Hui-jun~1 Cui YOU~2 Zhou Chong~1 et al (ISchool ofPharmaey,Yantai Univety,Yantai 2640057Zhejiang Tianrui Pharmaceutical Co.,Ltd,Ruian 325200,China);Diseussion About the Content Determinationof Essential Oil of Curcuma Wenyujin[A];[C];2011
3 ZHANG Jin-mei, ZHAO Wei-jie, WANG Shi-sheng (State Key Laboratory of Fine Chemicals ,Dalian University of Technology, Dalian 116012, China);Studies on chemical constituents of curcuma aromatica salisb[A];[C];2005
4 Jiang yuan Li zesong Jiang fusheng Deng xin Yao congshun Nie guang Shenzhen Shajing Hospital, Guangdong Shenzhen Yishengtang Biology Enterprise Company Jiang fusheng, Deng xin, Nie guang, Shenzhen Donghu Hospital, Guangdong Pharmacology office of Shenyang Pharmaceutial University;Investigating effects of different components of EZHU on gene expression of cultured HSC-T6 cells[A];[C];2006
5 Yuzhu Chen;Gaimei She;Department of Chinese Pharmacy,Beijing University of Chinese Medicine;;Research Progress of Curcumae Rhizoma[A];[C];2014
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 SHEN Shi-ren, SU Yin, HUANG Xiu-qing, XlE Zuo-fu,GAO Pin (Tumor Research Institute, Fujian Provincial Tumor Hospital, Fuzhau 350014);ESTABLISHMENT QF K562 CELL LINE RESISTANT TO ADM AND A PRELIMINARY OBSERVATION ON ITS CHARACTERISTIC BLOLOGY[J];Chinese Journal of Cancer;1992-03
2 Lou Jian′gang, Ren Zhiliang, Song Jiying, et al Sifang District Hospital, Qingdao 266033;EFFECT OF ELEMENE ON THE ERYTHROCYTE IMMUNE FUNCTION IN PATIENTS WITH MALIGNANT TUMORS[J];;1997-01
3 HAO Li-hong,LU Bu-feng,Yu Li-min (Department of Histology and Embryology,Dalian Medical University,Dalian,116027 China);Effect of β-elemene derivatve in combination with ADM on CEM/ADM cells growth[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;2000-03
4 Shi Guangxia et al(Department of Pathophysiology,Dalian Medical University);Experimental investigation on antitumor effect of β-elemene I In vitro cytotoxic effect of β-elemene on L615 leukemic cells[J];;1994-02
5 Liang Pin,et al(Department of Surgerg of The First Affiliated Hospital,Dalian Medical University);In vitro study on inhibitary effect of elemene combined with hyperthermia in H_(22)-F_(25)/L hepatomas[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;1995-01
6 Zou Lijuan,Li Jie,YuLimin,et alDepartment of Oncolgy,Second Hospital of Dalian Medical University;The antitumor activity of β-elemene associated with apoptosis[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;1998-02
7 Xu Xuejun, Zhou Zicheng, Luo Yuanhui, Lu Rong, Men Rongfu, Fang Dianchun (Department of Gasenterology, Southwest Hospital, Third Military Medical University, Chongqing, 400038);Elemene induced apoptosis of SMMC 7721 cells of human hepatocellular carcinoma[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;1999-04
8 Han Mingjun, Ren Ke, Zhao Zhongchun, et al. Department of Radiology, 1st Clinical College, China Medical University, Shenyang 110001;Oleum Curcuma Compound Used in Hepatic Arterial Embolization to Treat Hepatocellular Carcinoma: Follow up Report of 84 Cases[J];JOURNAL OF CLINICAL RADILOLGY;1998-02
9 Wang Jianzhong 1, Lou Yuefen 2, Lu Jinfang 2, He Xianping 3, Zheng Lixing 1, Deng Xiaolin 1 ( 1Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai 200032; 2Department of Pharmaceutics, School of Pharma;Gas chromatographic determination of curcumol on the microcapsules of combination curcuma oil[J];Chinese Journal of Clinical Pharmacy;2001-02
10 Hu Jiehan ; Cheng Guobao; Gong GuoliangWang Wanjun and Xu Yongting( Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023)( Centre of Experiment, Liaoning Normal University, Dalian 116029);~(13)C NMR SPECTRA OF THE PRODUCT OF THE CATALYTIC HYDROGENATION OF β-ELEMENE[J];CHINESE JOURNAL OF MAGNETIC RESONANCE;1997-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved