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《Acta Chimica Sinica》 1982-04
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EXCHANGE REACTION BETWEEN ACETOPHENONE AND BENZIMIDAZOLE N-MANNICH BASE

XU XIU-JUAN CHEN GUANG-XU(Department of Chemistry,Beijing Normal University)  
Aryl amine reacts with formaldehyde and benzoimidazole in ethyl alcohol to give arylamine-benzoimidazole N-Mannich base in good yield. Seventeen such bases, of which eight are new compounds, were prepared by this method. Arylamine-benzoimidazole N-Mannich bases undergo exchange reactions with acetophenone in the same manner as the N-Mannich bases from arylamines, formaldehyde and succinimide. These results provide a new method for preparing arylaminopropiophenones. It is proposed that the exchange reaction probably proceeds by an elimination-addition mechanism.
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Chinese Journal Full-text Database 5 Hits
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