Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chemical Research》 2007-03
Add to Favorite Get Latest Update

Synthesis and Thermosensitive Characterization of DTPA-Poly(N-isopropylacrylamide)

JIANG Shu-bin*,WANG He-yi,ZHONG Zhi-jing,YANG Yong(Institute of Nuclear Physics and Chemistry,China Academy of Engineering Physics,P.O.Box 919—215,Mianyang 621900,Sichuan,China)  
The thermosensitive poly(N-isopropylacrylamide)(PNIPAAm) aqueous solutions behave the low critical solution temperature(LCST) and could be used as drug delivery system.A novel drug delivery system based on PNIPAAm with isotopically labellable end groups DTPA has been designed and synthesized by reaction of 4,4′-azobis(4-cyanopentanoic acid),N-isopropylacrylamide,diethylenetriaminepentaacetic dianhydride and ethylenediamine.DSC measurements indicated DTPA-PNIPAAm showed similar LCST to that of PNIPAAm.DTPA-PNIPAAm enabled the delivery of therapeutic nuclides by PNIPAAm.
【Fund】: 中国工程物理研究院科学基金项目(20060537)
【CateGory Index】: O633.22
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 6 Hits
1 REN Yanrong~1 HUO Danqun~1 HOU Changjun~2 (1 Chongqing University Bioengineering College, Key Lab for Biomechanics & Tissue Engineering under the State Education Ministry, Chongqing 400044; 2 College of Chemistry and Engineering,Chongqing University, Chongqing 400044);Thermosensitive Poly(N-isopropylacrylamide) and Its Application[J];Materials Review;2004-11
2 LUO Yi(College of Chemistry and Molecular Engineering,Peking University, Beijing,100871) ZHUO Ren-Xi;FAN Chang-Lie(Department of Chemistry,Wuhan University, Wuhan, 430072);Studies on the Synthesis and Relaxivity of Amino Acids and Oligopeptides of Gd-DTPA Derivatives[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1995-09
3 He Qing Sheng Jing (Department of Material Scient & Engineering, Tian Jin University, Tianjin 300072);Properties of Responsive Hydrogels and Their Applications in Drug Controlled Release[J];JOURNAL OF FUNCTIONAL POLYMERS;1997-01
4 ZHOU Li,LU Zhi-yong,ZHANG Xi,DAI Hua(Polymer Research Institute of Sichuan University,State Key Laboratoryof Polymer Materials Engineering of China,Chengdu 610065,China);THE STUDIES ON THE TEMPERATURE SENSITIVE OF N-ISOPROPYLACRYLAMIDE COPOLYMER[J];Polymer Materials Science & Engineering;2006-02
5 QIN Ai-xiang~(1,2),LU Man-geng~1,LIU Qun-feng~(1,2),ZHANG Ping~(1,2) (1.Guangzhou Institute of Chemistry,Chinese Academy of Science,Guangzhou 501650,China;2.Graduate School of Chinese Academy of Sciences,Beijing 100039,China);Synthesis and Properties Study of Poly(N-isopropylacrylamide) Hydrogel with Fast Response Rate[J];Polymer Materials Science & Engineering;2006-05
6 Chen Yu,Chen Mingqing,Liu Xiaoya,Yang Cheng (School of Chemical and Material Engineering.Southern Yangtze University,Wuxi,214036);Temperatre-responsive Properties of Copolymers Having PNIPAAm Segment[J];Chinese Journal of Colloid and Polynier;2001-03
Chinese Journal Full-text Database 10 Hits
1 WANG Guo-ming,LIU Wen-bo,CAI Qing,JIN Ri-guang(Key Laboratory of Beijing City on Preparation and Processing of Novel Polymer Materials,College of Materials Science and Engineering,Beijing University of Chemical Technology,Beijing 100029,China);Preparation and Its Stability of Thermo-Sensitive Block Copolymer Nano-Micelles[J];Journal of Functional Polymers;2008-03
2 MAO Hua-hua1,GUAN Yin-yan1,QI Zai-qian1,SU Zhi-qiang1,2,SHI Shu-xian1,2,CHEN Xiao-nong1,2(1.Department of Biomaterials,College of Materials Science and Engineering,Beijing University of Chemical Technology,Beijing 100029,China;2.Beijing Novel Polymer Material Preparation and Processing Key Laboratory,Beijing 100029,China);Thermo-Sensitivity of N-Isopropylacrylamide Copolymers Containing Hydrophobic Units[J];Journal of Functional Polymers;2008-04
3 LU Diannan, LIU Zheng (Department of Chemical Engineering, Tsinghua University, Beijing 100084);TEMPERATURE SENSITIVE PNIPAAm ASSISTED PROTEIN REFOLDING in vitro[J];Acta Polymerica Sinica;2004-04
4 WU Yi-chun,GAO Bo,HOU Xin,YAO Kang-de(School of Materials Science and Engineering,Tianjin University,Tianjin 300072,China);The Preparation and Applications of Functional Polyacrylamide Microspheres[J];Polymer Materials Science & Engineering;2008-06
5 DONG Xiao chen, HE Ji dong, WANG Cun guo, GUO Hong ge (School of Polymer Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042,China);Newly Advances in Thermosensitive Hydrogel[J];Polymer Bulletin;2003-04
6 WANG Zhao yang\+\{1,2\}, ZHAO Yao ming\+\{*1\} (1 Institute of Materials, South China University of Technology, Guangzhou 510640, China; 2.Department of Chemistry, South China Normal University, Guangzhou 510631,China);Polyphosphate Esters Medical Materials[J];Polymer Bulletin;2003-06
7 QIU Jin-Jun~1,2,LIU Cheng-Mei~1*,HU Fen~1,GUO Xiao-Dong~3, ZHENG Qi-Xin~2,3 (1.Department of Chemistry,Huazhong University of Science and Technology;2.College of Life Science and Technology,Huazhong University of Science and Technology;3.Xiehe Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430074,China);Synthesis of Unsaturated Polyphosphoesteran Injectable Bone Tissue Engineering Scaffold Material[J];Chemical Research In Chinese Universities;2005-10
8 HU Hui, FAN Xiao dong (Department of Chemical Engineering, North Western Polytechnical University, Xian, 710072, China);Advance in Thermosensitivity Polymers Based on Poly(N isopropylacrylamide)[J];Journal of Functional Polymers;2000-04
9 Chen Xiao-ping,Li Na,Chen Hui-ming(Center for Analysis,Tianjin University,Tianjin 300072,China);Poly(N-isopropylacrylamide) Gel and Its Applicationin in Biomedical Engineering[J];Development and Application of Materials;2008-02
10 ZHENG Shu-Zhan, JIAN Ya-Jun, BAI Yin-Juan, XIE Zhan-Feng, CHANG Jian-Hua* (Department of Chemistry, Northwest University, Xi′an 710069, China);Synthesis, Relaxivity of Gd(Ⅲ), Fe(Ⅲ) and Mn(Ⅱ) Complexes with Dihydropyridine Derivatives of Diethylenetriaminepentaacetic Acid[J];Chemical Research In Chinese Universities;2004-09
China Proceedings of conference Full-text Database 1 Hits
1 Qin Wang, Chengru Zhao, Jianwen Meng, Xiaojie Zhu Institute of Medical Instruments of Shandong Province, Shandong Jinan 250100;SYNTHESIS AND CHARACTERIZATION OFA NEW THERMOSENSITIVE POLYMERS AS MEDICAL NONADHERE LIQUID EMBOLIC MATERIALS[A];[C];2004
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved