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《Chemical Research and Application》 2010-07
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Synthesis and structure of diorganotin phenoxy acetic acid containing silicon

LIN Sen1,XIAO Ling-hu1,JIANG Yu-chun1,DENG Feng-jie1,JIE Ke-min2,DENG Jian-yang1(1.Department of Chemistry,Nanchang University,Nanchang 330031,China;2.Medical College,Nanchang University,Nanchang 330031,China)  
Six diorganotin phenoxy acetic acid containing silicon were synthesized by the reaction of diorganotin oxides with phenoxy acetic acids;and their structures were characterized by IR,1HNMR,13CNMR,elemental analysis.The preliminary bioassay tests showed that(Me3SiCH2)2Sn(OCOCH2C6H4CH3-p)2 exhibited a good antitumour activity in vitro against lung tumour cells A549 and colorectal tumour cell SW480.
【Fund】: 国家自然科学基金(20762006)资助项目;; 江西省自然科学基金(2007JZH2103)资助项目
【CateGory Index】: O627.42
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