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《West China Journal of Pharmaceutcal Sciences》 2002-01
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STUDY ON RADIX ET RHIZOMA RHEI 'S EFFECTS ON CARIOGENIC BACTERIA IN VITRO

XIAO Yue, LIU Tian jia, HUANG Zheng wei,LI Ji yao,ZHOU Xue dong, ZHAN Ling West China College of Stomatology, Sichuan University, Chengdu 610041, China  
OBJECTIVE To study on the effects the role of Radix et Rhizoma Rhei on the growth, acidogenicity and glucan production of Streptococcus mutans, Streptococcus sanguis and Actinomyces viscosus as a preparation for screening an effective agent to mediate the balance of oral microflora. METHODS Streptococcus mutans 3a 3, Streptococcus sanguis SB 179 and Actinomyces viscosus ATCC 19246 were chosen as the experimental bacteria. Radix et Rhizoma Rhei were extracted by means of reflux extraction. Then the effects of Radix et Rhizoma Rhei on the growth, acidogenicity and glucan production were observed. RESULTS Radix et Rhizoma Rhei could inhibit the growth and acidogenicity of S.mutans, S.sanguis and A.viscosus , and the water insoluble glucan (WIG) production of S. mutans, effectively. CONCLUSION Radix et Rhizoma Rhei can inhibit the growth, acidogenicity and glucan production of oral bacteria, effectively.
【Fund】: UNILEVER公司英国研究中心资助项目
【CateGory Index】: R285
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