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《West China Journal of Pharmaceutical Sciences》 2004-02
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Synthesis of molecular imprinting polymer for Nicotinic acid

PU Jia - zhi, TANG You - wen, HU Xiao - gang, HUANG Zhao - fa, YAN Jing - hui (Department of Chemistry, South China Normal University , Guangzhou 510631, China; Department of Chemistry , Zunyi Medical College, Zunyi 563003, China)  
OBJECTIVE To synthsize a molecular imprinting polymer with Nicotinic acid as template.METHODS Different polymerization methods and different solvents were investigated to synthsize the imprinted polymer and the binding characteristics of the template polymer were evaluated by Scatchard analysis. RESULTS The polymer taking 4 - vinylpyndine as functional monomer and chloroform as solvent obtained higher selectivity for Nicotinic acid. CONCLUSION Molecularly imprinted polymer will exhibit practical utility for enrichment and determination of trace Nicotinic acid.
【Fund】: 贵州省科学基金资助课题 黔基台计号:(2003)3009号。
【CateGory Index】: R943
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