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《West China Journal of Pharmaceutical Sciences》 2004-03
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Determination of ligustilide in Ligusticum chuanxiong Hort.by HPLC

CHAO Zhen-zhen 1,CHAO Ruo-bing * (West China School of Pharmacy,Sichuan University,Chengdu,610041,China)  
OBJECTIVE To establish an HPLC method to determine ligustilide from Ligusticum chuanxiong Hort.METHODS The column were Luna 5 μ silica(2)(150 mm×4.6 mm ID);the mobile phase consisted of n-hexane-ethyl acetate-chloroform(92∶3∶5);the flow rate was 0.8 ml·min -1 and the UV detector was set at 320 nm.RESULTS The method displayed good linearity within the concentration ranges of 0.1-2.0 μg(r=1.0000).The average recovery were 100.7%.The contents of three lots of crude drugs were 1.55%,1.33% and 1.70%,respectively.CONCLUSION This method is simple,accurate,replicate and suitable for the determination of ligustilide in Ligusticum chuanxiong Hort.
【CateGory Index】: R284
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【References】
Chinese Journal Full-text Database 6 Hits
1 WANG Yi-meng,ZHANG Hui-fen,YAN Bao-qing,CHEN Xiao-hui,BI Kai-shun(School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);Determination of ferulic acid,6,7-di-hydroxyligustilide and 4-hydroxy-3-butylphthalide in Rhizoma Chuanxiong by HPLC[J];Chinese Journal of Pharmaceutical Analysis;2009-12
2 LIU Yun-hua1,YI Jin-hai1,SHAO Hua-wu2,CHEN Yan1,HUANG Zhi-fang1,LIU Yu-hong1(1.Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041,China;2.Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610041,China);Determination of butylphthalide and ligustilide in Chuanxiong Rhizoma by substitution method of reference substance[J];Chinese Journal of Pharmaceutical Analysis;2012-05
3 LI Yue-qin1,HUANG Hai-qin1,ZHOU Jiu-lan2(1.Chinese Medicine Hospital in Jiangyan City of Jiangsu Provinice,Jiangyan 225500,Jiangsu,China; 2.The Soviet Union in the Pharmaceutical Group,Jiangyan 225500,Jiangsu,China);Content Determination of Ligustilide in Zhuangyao Zhitong Ⅱ Mixture[J];Chinese Archives of Traditional Chinese Medicine;2012-11
4 LI Geng1,2,MENG Fan-yun2,YANG Hong-jun3,FANG Jing3, LIU Feng4,FU Mei-hong3*(1.National Integrative Medicine Center for Cardiovascular Diseases,China-Japan Friendship Hospital,Beijing 100029,China; 2.Beijing Key Laboratory for Protection and Utilization of Traditional Chinese Medicine,Beijing Normal University,Beijing 100875,China; 3.Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China; 4.Shaanxi Buchang Pharmaceutical Co.Ltd.,Xi'an 710075,China);UPLC simultaneous determination of five components in Naoxintong capsules[J];Chinese Journal of Pharmaceutical Analysis;2013-03
5 ZENG Hua-lan,YE Peng-sheng,HE Lian,LIU Zhao-hui,WEI Shu-gu,ZHANG Qian-fang,LI Qiong-ying,ZENG Jing(Industrial Crop Research Institute,Sichuan Academy of Agricultural Sciences,Sichuan Jianyang 641400,China);Effect of Trichoderma harzianum Preparation Treatment on Growth and Effective Components of Ligusticum chuanxiong[J];Southwest China Journal of Agricultural Sciences;2013-01
6 LYU Wei;WU Lian;LUO Hong-li;YE Na;WANG Chun-yan;FAN Cheng-jie;WAN Li;Key Laboratory of Standardization of Chinese Herbal Medicine, State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Ministry of Education, Department of Pharmacy, Chengdu University of Traditional Chinese Medicine;;Optimization of extraction process of Ligusticum chuanxiong by central composite design-response surface method[J];Drug Evaluation Research;2014-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 XIE Xiaomei,WANG Dian lei,ZHENG Rong qing,ZHOU Cui lan,YANG Fei xue (Dept. of Pharmacy,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230038,China);CONTENT DETERMINATION OF LEAD,CADMIUM,MERCURY AND ARSENIC IN DIFFERENT PARTS OF PRUNELLA VULGARIS AND DIOSCOREA OPPOSITA[J];Journal of Anhui Traditional Chinese Medical College;2002-05
2 Du Tinghai et al. (The 1st Affiliated Hospital of Henan College of TCM, Henan);Clinical and Experimental Study of Treatment of Angioneurotic Headache with “Toutong Yixiouning”[J];China Journal of Traditional Chinese Medicine and Pharmacy;1997-01
3 SHANG Li-zhi,WEI Da-wen,WANG Feng(Henan College of TCM,Zhengzhou 450008,China);Effects of ligustrazine on expression of HSP25 and p38MAPK proteins in rats with myocardial ischemia reperfusion injury[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-10
4 XIAO Yong-qing,ZHANG Cun,LI Li (Institute of Chinese Materia Madica,China Academy of Chinese Medicial Sciences,Beijing 100700,China);Quality assessment and administration for classified specifications with the high quality and favorable price about processing Chinese material medica[J];China Journal of Traditional Chinese Medicine and Pharmacy;2011-02
5 LIANG Zhong yan 1;NI Xiu zhen 2 (1 Life Sciences College of the Northeast Normal University,Changchun JiLin,130024 China; 2 Biology Department of Changchun Teachers College,Changchun JiLin,130032 China);The study on Application of Polysaccharide in Chinese Herb[J];Journal of Changchun Teachers College;2001-02
6 Kong Liang, Yu Zhiyuan, Zou Hanfa *, Sun Naichang, Wu Lihua, Ni Jianyi (National Chromatographic Research & Analysis Center, Dalian Institute of Chemical Physics,Chinese Academy of Sciences, Dalian 116011);Determination of the Active Ingredients in Rhizoma Chuanxiong by High Performance Liquid Chromatography Mass Spectrometry[J];Chinese Journal of Analytical Chemistry;2004-11
7 Li Li-Jun 1, Feng Jun2, Cheng Hao1, Chen Qi-Feng2, Zhong Zhao-Heng2, Kong Hong-Xing1, Wu Jian-Ling2 1(Department of Biological and Chemical Engineering, Guangxi University of Technology, Liuzhou 545006) 2(College of Chemistry and Chemical Engineering, Guangxi University, Nanning 530005);Separation and Determination of Salicylic Acid,Cinnamic Acid, Ferulic Acid and Vanillic Acid with Sample Stacking-Non-aqueous Electrophoresis[J];Chinese Journal of Analytical Chemistry;2007-03
8 SUN Guang-ping~(1,2),YANG Xue-dong~(*1),WANG Qiao-e~3 and DING Ming-yu~3(1.College of Pharmaceuticals & Biotechnology,Tianjin University,Tianjin 300072;2.China National Academy of Nanotechnology & Engineering, Tianjin 300457;3.Department of Chemistry,Tsinghua University,Beijng 100084);Quantitative determination of total senkyunolides in Rhizoma Chuanxiong by UV spectrophotometry[J];Chinese Journal of Analysis Laboratory;2007-01
9 JIANG Xiao-han,FENG Yi-fan,LIANG Han-ming,GUO Xiao-ling,MENG Qing (Institute of Materia Medica,Guangdong College of Pharmacy,Guangzhou,Guangdong 510006,China);HPLC analysis of butylidenephthalide in Szechwan lovage rhizome from different habitats[J];Journal of Guangdong College of Pharmacy;2006-06
10 DENG Xiao-hui,LI Shu-xian,WANG Ting,ZHANG Dan,LIANG Sheng-wang(School of Traditional Chinese Medicine,Guangdong College of Pharmacy,Guangzhou,Guangdong 510006,China);Optimization of the extraction procedure for the preparation of Sanxianzhuanggu capsules[J];Journal of Guangdong College of Pharmacy;2008-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 XU Na,CHEN Hai-sheng* Department of Natural Medicinal Chemistry,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Quantitative analysis of multi-components with single marker in simultaneous determination of 3-n-butylphthalide, sedenenolide,and sedanolide in celery seed extract[J];Academic Journal of Second Military Medical University;2013-02
2 CHEN Yan;YANG Hui;WANG Fu-hua;ZHU Ying;GENG An-jing;Public Monitoring Center for Agro-product, Guangdong Academy of Agricultural Science;Key Laboratory of Testing and Evaluation for Agro-product Safety and Quality, Ministry of Agriculture;Hubei Institute for Food and Drug Control;;The Rapid Determination of Total Mercury in Health Food by Direct Mercury Analyzer[J];Modern Food Science and Technology;2014-02
3 ZHANG Jinxia;DU Xiaoxia;CAO Fengqiu;LI Guofeng;ZHAO Ningmin;Department of Pharmacy, Henan Province People's Hospital;;Determination of Ferulic acid, and Caffeic acid in Rhizoma Chuanxiong. by HPLC[J];China Medicine and Pharmacy;2014-21
4 LI Yu;LI Chun;Guangzhou university of Chinesee Medicine;;The best extraction process of leeches anticoagulant components by central composite design-responsesurface methodology[J];Clinical Journal of Traditional Chinese Medicine;2015-04
5 LI Xue;QIN Yi-ting;LI Geng;DONG Xue-hui;College of Agriculture and Biotechnology,China Agricultural University;National Integrative Medicine Center for Cardiovascular Diseases,China-Japan Friendship Hospital;Beijing Key Laboratory for Protection and Utilization of Traditional Chinese Medicine,Beijing Normal University;;Study on Yield and Quality of Ligusticum jeholense in Different Harvest Seasons and Growth Years[J];Northern Horticulture;2015-11
6 GUO Zhi-feng,WANG Lei,GUO Ting-ting,SONG Cai-yu,ZHANG Li-xia(Key Laboratory of Analytical Science and Technology of Hebei Province,Research Center of Physical and Chemical Analysis,Hebei University,Baoding 071002,China);GC-MS Analysis of Chemical Constituents Extracted from Ligusticum chuanxiong Hort. by Ultrasonic Extraction[J];Journal of Hebei University(Natural Science Edition);2009-02
7 JIANG Wei-dong1,TANG Lin1,YANG Cang-jin1,MA Yu-ying2,JIANG Gui-hua2,CHEN Fang1 (1.College of Life Sciences,Sichuan University,Chengdu 610064,China;2.School of Pharmacology,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China);Effects of Kanamycin on the Induction and Growth of Ligusticum chuanxiong Hort.Callus[J];Journal of Henan Agricultural Sciences;2007-11
8 CAI Qin,LIANG Long,HOU Shi-xiang,HUANG Yan-ping.Postdoctor Mobile Station,West China School of Pharmacy,Sichuan University,Chengdu 610041,China;Preparation of Self-microemulsifying Drug Delivery System for Volatile Oil from Rhizome of Ligusticum Chuanxiong[J];Journal of Sichuan University(Medical Science Edition);2008-02
9 LIU Yun-hua,YI Jin-hai*,HUANG Zhi-fang,LIU Qian-ling,CHEN Yan,LIU Yu-hong (Sichuan Academy of Chinese Medicine Sciences,Chengdu,Sichuan,610041 P.R.China);Determination of total senkyunolides in the oil of Ligusticum Chuanxiong Hort.by UV spectrophotometry[J];West China Journal of Pharmaceutical Sciences;2009-04
10 WANG Ping1,WANG Chen2,LOU Yiceng2(1.Hubei University of Chinese Medicine,Wuhan 430061,Hubei,P.R.China; 2.Wuhan University of Science and Technology,Wuhan 430070,Hubei,P.R.China);Borneol and Rhizome of Chuanxiong on Facilitating Permeation for Compound Shuyu Jiannao Decoction through Blood Brain Barrier[J];Journal of Hubei University of Chinese Medicine;2011-05
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