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《West China Journal of Pharmaceutical Sciences》 2007-05
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Isolation and identification of triterpenoid saponins from Patrinia scabiosaefolia Fisch

LI Yan-fang1,LOU Feng-chang 2(1.Department of Pharmaceutics and Bioengineering,Sichuan University,Chengdu 610065,China;2.Department of Natural Medicinal Chemistry,China Pharmaceutical University,Nanjing 210038,China)  
OBJECTIVE To investigate the chemical constituents of the whole plant of Patrinia scabiosaefolia Fisch.METHODS Column chromatography(including D101 macroporous resin,silica gel and ODS) was used to separate the chemica1 constituents in the ethanol extract of the whole plant.The constituent structures were elucidated by ESI-MS,NMR(1D and 2D) spectroscopic analysis and hydrolysis methods.RESULTS Six compounds were isolated and identified as prosapogenin CP3(Ⅰ),sieboldianaside A(Ⅱ),hederasaponin C(Ⅲ),3-O-β-D-xylopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-β-D-glucopyranosyl ester(Ⅳ),giganteaside D(Ⅴ) and sapindoside A(Ⅵ),respectively.CONCLUSION Compound Ⅳ is a new natural product.Compounds Ⅰ and Ⅲ were isolated from this plant for the first time.
【CateGory Index】: R284
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