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《West China Journal of Pharmaceutical Sciences》 2009-04
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Studies on immunomodulation of polysaccharide from Arca subcremata Lischke

WANG Li1,HE Yun-mian2,YAO Quan-sheng3* (1.Nanjing University of Technology,Nanjing,Jiangsu,210009 P.R.China;2.China Pharmaceutical University,Nanjing,Jiangsu,210009 P.R.China;3.Jiangsu Center for Safety Evaluation of Drugs,Nanjing,Jiangsu,210009 P.R.China)  
OBJECTIVE To study the effects of polysaccharide from Arca subcremata Lischke(ASLP) on immunologic function in normal mice.METHODS The cell multiplication of splenic lymphocyte and T,B lymph cell in vitro were studied.The body weight,the index of immune organs and carbon granula test were used to determine the effect of ASLP on immune function in vivo.RESULTS The in vitro tests shewed that ASLP could enhance the ability of cell multiplication of splenic lymphocyte and T,B lymph cell compared with controll group.CONCLUSION The results indicated that ASLP could improve the immunological function of mice.It could be a good immunomodulater.
【CateGory Index】: R285.5
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