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《West China Journal of Pharmaceutical Sciences》 2009-06
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Determination of cinnamaldehyde and cinnamic acid in Cinnamon formula granule by HPLC

CHENG Cha-qun1,WEI Yan-hua1,TAN Xiu-fen1,ZENG Rui2 ( 1. Affiliated Hospital of Fangcun Third Branch Guangzhou University of Chinese Medicine,Guangzhou,Guangdong,510045 P. R. China; 2. Ethnic Pharmaceutical of Southwest University for Nationalities,Chengdu,Sichuan,610041 P. R. China)  
OBJECTIVE To establish a method to determine cinnamaldehyde and cinnamic acid in Cinnamon formula granule. METHODS HPLC method was adopted. ODS column( 250 mm × 4. 6 mm,5 μm) of Hydrosphere with the mobile phase containing a mixture of acetonitrile water -0. 1% phosphoric acid solution ( 35: 25: 40) ,with a flow rate of 1. 0 mL·min -1,and the wavelength at 287 nm,were utilized for this study. RESULTS The method could quantitatively determine cinnamaldehyde and cinnamic acid in Cinnamon formula granule. The linear range of cinnamaldehyde was 0. 75 7. 50 μg ( r = 0. 9995) and the average recovery was 98. 2% with RSD of 1. 61% . The linear range of cinnamic acid was 0. 22 1. 32 μg( r = 0. 9992) and the average recovery was 97. 9% with RSD of 1. 32% . CONCLUSION The method is accurate,sensitive and can be used to control the quality of Cinnamon formula granule.
【Fund】: 广州中医药大学校基金项目(项目编号:06C078)
【CateGory Index】: R286.0
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 LIN Jia, XU Li-zhen, LIU Jiang-yun, ZOU Zhong-mei( Institue of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China);Study on contents of cinnamaldehyde and cinnamic acid and distribution of Ramulus Cinnamomi[J];Chinese Pharmaceutical Journal;2005-23
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SHAN Bao-en,LI Jun-xin,ZHANG Jing,LIANG Wen-jie,LI Hong-fen(Science and Research Center,The Fourth Hospital of Hebei Medical University,Hebei Shijiazhuang050011,China);The Anti-tumor in Vitro Effect of Cortex Periplocae and Its Analogues Extracted[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-05
2 LU Wen-yun et al (College of Chemistry and Environment, Guizhou University for Nationalities, Guiyang, Guizhou 550025);Compared Analysis of Total Alkaloids and Polysaccharides in Tubing Shoot and Wild Plant of Dendrobium Loddigesii[J];Journal of Anhui Agricultural Sciences;2006-08
3 TIAN Shi-lin et al (Huanghuai University,Zhumadian,Henan 463000);Determination and Comparison of Chlorogenic Acid in Leaf and Bark of Cortex[J];Journal of Anhui Agricultural Sciences;2006-13
4 YIN Shuai-wen et al(College of Life Science,Jinggangshan University,Ji'an,Jiangxi 343009);Study on Traditional Poisonous Pteridophyte in Jinggangshan Region[J];Journal of Anhui Agricultural Sciences;2007-08
5 WU Gong-qing et al (Guangdong Pharmaceutical University, Guangzhou, Guangdong 510006);Study on the Extraction of Total RNA from Pinellia ternata (Thunb.) Berit Leaves[J];Journal of Anhui Agricultural Sciences;2008-08
6 ZHANG Xu et al(College of Agronomy,Sichuan Agricultural Universty,Yaan,Sichuan 625014);The Determination of Vitamins in the Leaf of Perilla L.by HPLC[J];Journal of Anhui Agricultural Sciences;2008-19
7 LI Jin-bu et al (Life Sciences College of Huaibei Coal Industry Teachers College,Anhui Biology Key Laboratory of Resource Plant,Huaibei,Anhui 235000);Studies on Bioactivity of Extracts from Pinellia ternata (Thunb.) Breit on Myzus persicae(Sulzer)[J];Journal of Anhui Agricultural Sciences;2009-09
8 ZHAO Hong-yan et al(Department of Life Sciences and Technology,Xinxiang University,Xinxiang,Henan 453000);Changes of Eucommia ulmoides Leaf in Organization Structure and Index Component Contents during Its Growth and Development Process[J];Journal of Anhui Agricultural Sciences;2009-14
9 XING Bing-cong et al(College of Forestry and Biotechnology,Zhejiang Forestry University,Hangzhou,Zhejiang 311300);Progress in Curcumin Derivatives form Curcuma wenyujin[J];Journal of Anhui Agricultural Sciences;2009-16
10 DING Qing1,WU Yue 1,XU Yi-liang2,LIU Xiu-qin2,TANG Bo2(1.Jiangsu Institute for Drug Control,Wuxi 214021;2.Jiang Yin Tian Jiang Pharmaceutical Co.,Jiangyin Jiangsu 214434,China);Determination of six harmful trace elements in fructus corni by ICP-OES[J];Anhui Medical and Pharmaceutical Journal;2008-01
China Proceedings of conference Full-text Database 8 Hits
1 Zhang Chunhui,Wu Aiying,Wang Youlan (Qingdao Institute for Drug Control,Shandong Province,Qingdao 266071);Identification on Radix Puerariae thomsonii and its adulterant Radix Puerariae edulis[A];[C];2008
2 WANG Hai-yan JI Yu-bin LI Wen-lan HU Zheng-ting YU Ying-Ying(Center of Research on Life Sciences and Environmental Sciences,Harbin University of Commerce,Harbin China 150076,;Engineering research center of natural anticancer drugs,ministry of educatuion,Harbin China 150076);Study on influencing factors of percutaneous absorption of cinnamic acid[A];[C];2008
3 Li Wenlan1,2,YU Yingying1,2,Ji Yubin1,2,Ren Xiaolei 1,2,XU Dong1,2(1.Center of Research and Development on Life Sciences and Environmental Sciences,Harbin University of Commerce,Harbin 150076,China,2.Engineering Research Center of Natural Anticancer Drugs,Ministry of Education,Harbin University of Commerce,Harbin 150076,China);Study on Relationship between Metabolism of Cinnamic Acid and Cytochrome P450[A];[C];2008
4 LIANG Man~1 LIU Yan~1 ZHENG Na~1 ZHOU Lan~1 YANG Fan~1 HUANG Guang-zhao~1 LIU Liang~2 (1.Faculty of Forensic Medicine,Tongji Medical College,Huazhong Science and Technology University,430030,Wuhan;2.Key Laboratory of Evidence Science(China University of Political Science and Law),Ministry of Education,100040,Beijing);Study of Toxicology of Sixangular Dysosma Rhizome[A];[C];2009
5 Lu Xiao-xia~1,Jiang Li-jia~1,Fan Jing~1,Wang Duo-qin~1,Tang Min~1,Xia Lei~1,Ma Ling-di~(1,*) 1 Changzhou Second Hospital,Nanjing Medical University,Changzhou 213003;2 The first clinical college,Nanjing Medical University,Nanjing 210029;Effect of matrine on proliferation inhibition and apoptosis induction in K562 cells in vitro[A];[C];2009
6 Wu Lihong,Wang Zhengtao (Shanghai R&D Center for Standardization of Chinese Medicines,Shanghai 201210,China; The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines,Institute of Chinese Materia Medica,Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China);Inheritance of Chinese Gentian Root[A];[C];2010
7 ;Analysis on cultivation influence on Genetic Diversity of authentic Glycyrrhiza uralensis[A];[C];2010
8 Xiaoli Zou 1 , Yuanyuan Chai 1 , Li Yang 2 , Hui Xu 1 , Xin Che 1 , and Ke Liu 1, 3 1) School of Pharmacy, Yantai University, Yantai, China 2) School of Chemistry and Chemical Engineering, Shenyang University of Chemical Technology, Shenyang, China 3) Shandong Target Drug Research Co. Ltd., Yantai, China;Effects of Hydroxynaphthoquinones from Radix Arnebia on Liver CYP2D6 in Rat[A];[C];2010
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 WANG Tao1*, JIN Ge2, WANG Shu mei1, et al 1 Department of Respiratory Medicine, the First Affiliated Hospital, Henan Medical University, Zhengzhou 450052, P R China 2 The School of Basic Medical Sciences, Henan Medical University, Zhengzhou 450052,;Induced differentiation of human lung adenocarcinoma cells by cinnamic acid[J];CHINESE JOURNAL OF CANCER;2000-08
2 HUANG Wei,HUANG Ji qun,ZHANG Dong fang,et al. Cancer Research Institute,Guangzhou Medical College,Guangzhou,510182;Differentiation of BEL-7402 Human Hepatocarcinoma Cells Induced by Cinnamic Acid[J];THE PRACTICAL JOURNAL OF CANCER;2000-01
3 Huang Wei, Hu Meixiang (Cancer Research Institute, Guangzhou Medical College, Guangzhou, 510182);The Effects of Cinnamic Acid on Proliferation and Nucleolar Organizer Regions of PGCL3 Human Lung Cancer Cell[J];THE PRACTICAL JOURNAL OF CANCER;1997-03
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