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《West China Journal of Pharmaceutical Sciences》 2015-04
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Determination of imperatorin and isoimperatorin in Tianma Toutong tablets by UPLC

HE Dan;YANG Lin;ZHANG Jing-qing;College of Pharmacy,Chongqing Medical University;Department of Pharmacy,Chongqing Medical and Pharmaceutical College;  
OBJECTIVE To establish an Ultra Performance Liquid Chromatography method for determination of imperatorin and isoimperatorin in Tianma Toutong tablets( TTT). METHODS Acquity UPLC BEH Cl8column( 50 mm × 2. 1 mm,1. 7 μm) was used,and the mobile phase was methanol and water by gradient elution mode with the column temperature of 30 ℃,a flow rate of 0. 3 m L·min- 1and detection wavelength of 248 nm. RESULTS The linear range of imperatorin was 1. 305- 26. 10 μg·m L- 1,the regression equation was Y = 1. 3448 × 104 X + 952( r = 0. 9999). The linear range of isoimperatorin was 0. 596- 11. 92 μg·m L- 1,and the regression equation was Y = 1. 0331 × 104 X + 588( r = 0. 9999). The average recovery was 98. 98%( RSD = 0. 87%) and 99. 07%( RSD =1. 09%),respectively. CONCLUSION The method is accurate,rapid and reliable,and can be used to determine imperatorin and isoimperatorin in TTT.
【CateGory Index】: R286.0;O657.72
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【Citations】
Chinese Journal Full-text Database 4 Hits
1 Chen Jian-feng~1,Yuan Zi-min~2,Wang Jing~2 (1 Liaoning Chengda Fangyuan Medicine Chained Limited Company,Shenyang 110005,China; 2 Liaoning university of TCM,Dalian 116600,China);Determination of Ferullic Acid in Tianmatoutong Tablet by RP-HPLC[J];Chinese Journal of Medicinal Guide;2011-02
2 JIA Min-ru,WANG Meng-yue,JIN Qu-mo,MA Yu-ying,TANG Sheng-wu,XIONG Ying,JIANG Gui-hua School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Determination of imperatorin and isoimperatorin in Radix Angelicae dahuricae by HPLC[J];West China Journal of Pharmaceutical Sciences;2003-05
3 CHEN Xiao - liang;RUAN Jia;XU Chao - qun;YUAN Zhi - xiang;WANG Li - zhen;BIAN Jun - jie;College of Pharmacy,Chengdu University of Traditional Chinese Medicine;Sichuan Academy of Chinese Medicine Sciences;;Study on the purification procedure of Cassiae semen and Angelica dahuricae in Zhigui tablets[J];West China Journal of Pharmaceutical Sciences;2014-01
4 GAO Jian - Hui,FENG Hui - lian (Shenyang Red Cross Hospital,Shenyang 110013,Liaoning,China);Tianma Toutong Tablet Treatment of 29 Patients with Vascular Headache[J];Journal of Practical Traditional Chinese Internal Medicine;2010-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 FENG Hui-ping,HE Sheng-li,NING Kang-jian(1.Tianjin Pharmaceutical Group Xinzheng Co.,Ltd.,Xinzheng 451150,China;2.Anhui Science and Technology University,Fengyang 233100,China);Determination of Geniposide in XEFRQKL by HPLC[J];Journal of Anhui Science and Technology University;2009-04
2 GAO Ying,MA Yu-ying,ZHONG Shi-hong,et al(1.College of pharmacy,Chengdu University of Traditional Chinese Medicine Chengdu,610075,China 2.Chengdu Medical College,Chengdu,610083,China);Comparison on Determination of Imperatorin in Radix Angelicae Dahuricae[J];Journal of Chengdu University of Traditional Chinese Medicine;2006-04
3 TANG Fu-lin1,LI De-nan2,WEI Cui-ji2,CHEN Chao-feng2(1.Guangxi Huahong Pharmaceutical Co.,Ltd.,Liuzhou 545007,China;2.Guangxi Naning Runshang Medical Technological Devenlepment Limited Corporation,Nanning Engineering Research Center,Nanning 530219,China);Determination of Imperatorin in Kelisha Pellets by HPLC[J];Journal of Guangxi University of Technology;2011-02
4 ZHU Li-qiao,SHENG Hua-gang(Shandong University of Traditional Chinese Medicine,Shandong Jinan 250355,China);GC-MS Analysis on Volatile Components of Radix Angelica Dahuricate[J];Guangzhou Chemical Industry;2012-23
5 Wang Xueying1,2,Lu Sheming1,Zhu Li1,Meng Zhaoyu1,Cao Qiue2 [1.R&D Center of Hongta Tobacco(Group) Co.Ltd.,Yuxi 653100,China; 2.College of Chemical Science and Engineering,Yunnan University,Kunming 650091,China];DETERMINATION OF IMPERATORIN IN TOBACCO FLAVOR BY RP-UPLC[J];Chemical Analysis and Meterage;2011-06
6 CHEN Jie1,LI Zhan1,HUANG Qing-quan2(1.Henan Provincial Institute for Drug Control,Zhengzhou 450003,China;2.National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050,China);Identifications of medicinal and determination of imperatorin in Fuwei San capsules[J];West China Journal of Pharmaceutical Sciences;2007-04
7 PAN Xiao-juan1,2,SHEN Li2(1.West China School of Pharmacy,Sichuan University,Chengdu 610041,China;2.Sichuan Institute of Chinese Materia Medica,Chengdu 610041,China);Determination of imperatorin in Zhongtongxiao paint by HPLC[J];West China Journal of Pharmaceutical Sciences;2007-05
8 Wan Yan Ma Guozhu Feng Suxiang Henan University of Traditional Chinese Medicine,Zhengzhou Henan China 450046;Determination of Imperatorin and Isoimperatorin in Radix Angelicae Dahuricae[J];China Journal of Chinese Medicine;2013-08
9 WANG Xiao-yan;Anyang City,Henan province food and Drug Inspection Institute;;Different manufacturers quality analysis of angelica dahurica[J];Journal of Clinical Medical Literature;2015-02
10 Wu Boying ( Liangshan Institute of Food and Drug Control, Liangshan, Sichuan 615000) Li Min, Liuwei, Lilixia, Liuyu (Chengdu University ofTCM, Chengdu, Sichuan 610075};Determining Imperatorin in Yishen Capsule Using HPLC[J];;2006-05
China Proceedings of conference Full-text Database 2 Hits
1 HE Ge-fei,Yi Ai-chun,Zhang shun-zhi(First hospitol of changsha, changsha,410005);Determination of Imperatorin in Qinxuan Pills by HPLC[A];[C];2009
2 HE Ge-fei,Yi Ai-chun,Zhang shun-zhi(First hospitol of changsha,changsha,410005);Determination of Imperatorin in Qinxuan Pills by HPLC[A];[C];2010
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHAO Wan-hong,CAO Yong-xiao,LIU Jing,et al(Dept of Pharmacology of Yunyang Medical College,Shiyan 442000,China);Research on chronic toxicology of Compound Radix Angelicae Dahuricae capsule[J];Journal of Shanxi Medical University;2006-02
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