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《West China Medical Journal》 2008-06
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Clinical Analysis of 21 Cases with Aspergillus Infection

FENG Fang,YIN You-kuan,CHEN Yi-dong,et al.(1.The First College of Clinical Medical Science,China Three Gorges University;2.The Department of Liver Disease,Yichang Central People's Hospital,Hubei Yichang 443000 China;3.Infectious Department of Huashan Hospital Affiliated to Fudan University,Shanghai 200040,China)  
Objective:To assess the clinical manifestations,diagnosis and treatment of aspergillosis infection.Methods:The data of 21 patients were reviewed,including general status,clinical manifestations,laboratory findings,diagnosis,treatment and prognosis.Results:Among 21 case,16 cases were 50 years old or more than 50 years old,19 cases suffered from two or above two underling diseases(90.5%),the common underling diseases were COPD,chronic liver disease,rheumatic disease.Itraconazole was a effective treatment for the patients with aspergillosis infection.Conclusion:It's important to be on guard against aspergillosis infection to the elderly with long-time hospitalization,especially those treated by cortical homone,immunosuppressant or polyantibiotic.Culture combined with direct microscopic examination could help to diagnose and manage aspergillosis infection at an earlier stage in the disease process.
【CateGory Index】: R519.8
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