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《Oceanologia et Limnologia Sinica》 2012-02
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EFFECTS OF CADMIUM ON APOPTOSIS OF CARDIOMYOCYTE IN THE FRESHWATER CRAB SINOPOTAMON YANGTSEKIENSE

LEI Wen-Wen,XU Tuan,WANG Lan(School of Life Science,Shanxi University,Taiyuan,030006)  
The effects of cadmium(Cd) on cardiomyocyte apoptosis in the freshwater crab Sinopotamon yangtsekiense were investigated by acute systemic toxicity testing methods.To verify if apoptosis is one of the cardiomyocyte death pathways upon Cd administration,crabs were exposed to different concentrations of Cd(0,7.25,14.50,29.00,58.00 and 116.00 mg/L) for 1,3,5 and 7 days.The results of hematoxylin and eosin(H.E.) staining assays showed that there were no obvious alterations in cardiac histology of crabs in low concentrations and short-term exposure groups.With increasing Cd concentrations and exposure time,histological abnormalities appeared including vacuolar and vitreous degeneration,and infiltration of inflammatory cells.Apoptosis-like cells were observed,but rare in 7d exposure groups.Besides,the characteristic apoptotic morphologic changes and "ladder" pattern weren't observed by fluorescence microscopy with Hoechst 33258 staining and agarose gel electrophoresis.Flow cytometry assay indicated that the percentage of apoptotic cells were increased with the increasing of exposure time and concentrations of Cd compared with control,but there was no significant difference.Moreover,the activity of Caspase-3 was not affected by Cd treatment after 7 days exposure.However,these findings suggest that apoptosis wasn't induced by Cd in cardiomyocyte in the present study.While previous studies in our lab showed that Cd induced apoptosis in the hepatopancreas and testis cells of crabs after 2 days and 7 days exposure.In crab cardiomyocyte,the lack of Cd-induced apoptosis may be attributed to different Cd accumulation amount in the three tissues.
【Fund】: 国家自然科学基金资助项目 30870267号 30970361号;; 山西省自然科学基金资助项目 2008011069号
【CateGory Index】: X174
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【References】
Chinese Journal Full-text Database 1 Hits
1 DU Li-na,YU Ruo-zhen,WANG Hai-yan,LU Yun,LIU Zheng-tao.State Key Laboratory of Environmental Criteria and Risk Assessment,Chinese Research Academy of Environmental Sciences,Beijing 100012,China;Pollution and toxicity of cadmium: a review of recent studies[J];Journal of Environment and Health;2013-02
【Citations】
Chinese Journal Full-text Database 8 Hits
1 WANG Lan YANG Xiu-Qing WANG Qian WANG Ding-Xing (Life Science,Shanxi University,Taiyuan 030006,China);THE ACCUMULATION OF Cd~(2+) AND THE EFFECT ON EST IN FIVE TISSUES AND ORGANS OF ERIOCHEIR SINENSIS[J];Acta Zoologica Sinica;2001-S1
2 WANG Hua,HUANG Wei,SUN Lei,GUO Cai-xia,JIN Ming-hua,LIU Xiao-mei,WANG Wen, SUN Zhi-wei(Department of Toxicology,School of Public Health,Jilin University,Changchun 130021,China);Mechanism of apoptosis in rat H9c2 cells induced by cadmium chloride[J];Journal of Jilin University(Medicine Edition);2007-02
3 Wang Qiang; Yao Sumei; Guo Xiuling (Kaifeng Medical College, Kaifeng 475001);Distribution of Cadmium in Main Organs of Acute Cadmiun Poisoned Rats[J];TRACE ELEMENTS SCIENCE;1998-09
4 LI Jing1,YAN Bo2,LIU Na3,WANG Qian1,WANG Lan1,1. School of Life Science,Shanxi University,Taiyuan 030006 2. School of Basic Medical Sciences,Fourth Military Medical University,Xi'an 710032 3. The Key Laboratory of Mariculture,Ministry of Education,Ocean University of China,Qingdao 266003;Effects of cadmium on apoptosis of hepatopancreas cell in freshwater crab, Sinopotamon yangtsekiense[J];Acta Scientiae Circumstantiae;2010-11
5 LU Jian-Feng1,2,CHANG Guo-Liang2,3,WU Xu-Gan2,YANG Xiao-Zhen2,ZHAO Wei-Xin2,CHENG Yong-Xu2(1.School of Biotechnology and Food Engineering,Hefei University of Technology,Hefei,230009;2.Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources,Shanghai,201306;3.School of Life Sciences,Huaiyin Normal University,Huaiyin,223300);HORMONAL REGULATIONS OF OVARIAN DEVELOPMENT AND VITELLOGENESIS IN CHINESE MITTEN CRAB ERIOCHEIR SINENSIS FED ON TWO DIFFERENT DIETS[J];Oceanologia Et Limnologia Sinica;2010-04
6 YANG Ji-Fang1, 2, 3, GUO Lu-Yun1, 2, 3, CHEN Fu-Sheng1, WANG Hai-Li2, 3 (1. College of Foods Science & Technology, Huazhong Agricultural University, Wuhan, 430070; 2. Municipal Key Laboratory of Microorganism and Environmental Engineering, Ningbo, 315100; 3. Faculty of Biological & Environmental Science of Zhejiang Wanli University, Ningbo, 315100);THE EFFECTS OF LIPOPOLYSACCHARIDES FROM TWO STRAINS OF OLIGOTROPHIC BACTERIA FROM ANTARCTIC OCEAN ALTEROMONAS STELLIPOLARIS ON NON-SPECIFIC IMMUNITY OF THE SWIMMING CRAB PORTUNUS TRITUBERCULATUS[J];Oceanologia Et Limnologia Sinica;2011-02
7 Zhao Wei,Wang Qiang(Hennan University ,Kaifeng 475001,China);Effects of Cadmiun on DNA Damage of Cardiomyocytes and Liver Cells in Mice[J];Journal of Labour Medicine;2005-06
8 WANG Qian 1,WANG Lan 1,XI Yu-ying 2,YANG Xiu-qing 3,WANG Ding-xing 1 (1.Shool of Life Science and Technology ,Shanxi University,Taiyuan 030006,China;2.School of Envirnmental and Resource,Shanxi University,Taiyuan,030006,China; 3.Institute of Microviology,Chinese Academy of Sciences,Beijing 100080,China);The Acute Toxcity and Accumulated of Cd~(2+) in freshwater Crab Sinopotamon yangtsekiense[J];Journal of Shanxi University (Natural Science Edition);2003-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 DAI Zhong-hua,SHI Nian ,LIU Gong-ping,WEI Yan-hong LI Huang-yuan,CHEN Dan,WANG Bin (Department of Health Toxicology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan Hubei430030,China);The Effects of Deltamethrin on Fas,FasL,TNFR1 Protein Expre s sion and Apoptosis in PC12 Cells[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-02
2 LIN Li-na,LIN Yu-chun,CHEN Hui-feng,LUO Jie, LI Xiao-jie,HU Yao-ming,LI Wen, ZHANG Shu-jiang,CHEN Wen,LIN Zhong-ning~* (School of Public Health,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Food,Nutrition and Health,Guangzhou 510080,Guangdong,China);Overexpression of PP2A-B56γ repressed the effect of cadmium on DNA damage in human normal L02 liver cells[J];Carcinogenesis,Teratogenesis & Mutagenesis;2012-03
3 HUANG Qiu-chan et al(Department of Chemistry and Life Science,Nanning Teachers College,Longzhou,Guangxi 532400);Review on the Toxicological Effect and the Mechanism of Cadmium to Human Health[J];Journal of Anhui Agricultural Sciences;2007-09
4 ZHANG Ting et al (College of Biology Science and Technology,Shanxi University,Taiyuan,Shanxi 030006);Accumulation and Distribution of Copper in the Freshwater Crab,Sinopotamon honanense[J];Journal of Anhui Agricultural Sciences;2007-24
5 ZHAO Yue-ping et al (Department of Biology,Taiyuan Teachers College,Taiyua,Shanxi 030031);The Effects of Laundry Powder on POD and EST Isozyme in Blood of Misgurnus anguillicaudatus[J];Journal of Anhui Agricultural Sciences;2010-13
6 JIA Xiu-ying, DONG Ai-hua (School of Life Sciences, Hangzhou Normal College, Hangzhou 310036, China);Effects of Cd and Cr(VI)single and combined pollution on peroxidaes isozymes of carassius auratus[J];Journal of Safety and Environment;2004-02
7 WANG Ming-shu~1,2,CHENG An-chun~1,2,LIU Fang~1,3,CHEN Xiao-yue~1,LIU WU-mei~1(1.College of Animal Science & Veterinary Medicine,Sichuan Agricultural University,Yaan 625014,Sichuan,China;2.Key Laboratory of Animal Disease and Human Health of Sichuan Province,Yaan 625014,Sichuan,China;3.College of Animal Science & Veterinary Medicine,Henan Agricultural University,Zhengzhou 450000,Henan,China);Study on Dynamic Changes of Apoptosis of Host Cells after the Artificial Infection of Piglets by Porcine Reproductive and Respiratory Syndrome Virus[J];Chinese Journal of Virology;2006-05
8 WANG Lan ①** SUN Hai Feng ② LI Chun Yuan ③ (① College of Life Science and Technology, Shanxi University, Taiyuan 030006, Shanxi, China) (② Collleg of Chemistry Engineering, Shanxi University, Taiyuan 030006, Shanxi, China) (③ Ch;EFFECTS OF CADMIUM ON SPERMATOGENESIS IN FRESHWATER CRAB (SINOPOTAMON YANGTSEKIENSE)~*[J];Acta Zoologica Sinica;2002-05
9 CAI Ya-Fei 1,2, DU Juan1, ZHANG Li-Jun1, LI Lian1, LIU Qing-Hua1, ZHOU Lei1, YANG Yuan-Yuan1, WANG Gen-Lin 1**1.College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China2.College of Life Sciences, Anhui Normal University, Wuhu 241000 Anhui,ChinaExpression of apoptosis-related genes and blood index in lymphocytes in peripheral blood of dairy cows*$$$$ CAI Ya-Fei 1,2, DU Juan1, ZHANG Li-Jun1, LI Lian1, LIU Qing-Hua1, ZHOU Lei1, YANG Yuan-Yuan1, WANG Gen-Lin 1**1.College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China2.College of Life Sciences, Anhui Normal University, Wuhu 241000 Anhui,China;Expression of apoptosis-related genes and blood index in lymphocytes in peripheral blood of dairy cows[J];Acta Zoologica Sinica;2005-02
10 YAN Bo, WANG Lan , LI Yong-Quan, LIU Na, WANG QianCollege of Life Science and Technology, Shanxi University, Taiyuan 030006, China;Effects of cadmium on hepatopancreatic antioxidant enzyme activity in a freshwater crab Sinopotamon yangtsekiense[J];Acta Zoologica Sinica;2007-06
China Proceedings of conference Full-text Database 5 Hits
1 YU Feng-jun, LI Kang, LI Er-chao, CHEN Li-qiao, GUO-Hui School of lifesciences, ECNV, Shanghai, 200062, China;Acute toxicity and their joint toxicity effect of Pb~(2+),Cd~(2+) for the juvenile of Chinese mitten-handed crab(Eriocheir sinensis)[A];[C];2005
2 MENG Fan, WANG Lan, CHENG Xue-Ying, WANG Qian, ZHANG Ting, HAO Dong-Liang College of Life Science and Technology, Shanxi University, Taiyuan 030006, Shanxi, China China Institute for Radiation Protection, Shanxi University, Taiyuan 030006, Shanxi, China;Effects of cadmium on overy morphology of freshwater crab Sinopotamon henanense[A];[C];2005
3 ZHANG Xiao-Bo, WANG Lan, WANG Qian, HE Yong-Ji College of Life Science and Technology, Shanxi University, Taiyuan 030006, China;Effect of cadmium on activity of freshwater crab Sinopotamon henanense mitochondria enzymes[A];[C];2005
4 HUANG Yunmei,~*CHEN Wenlie,HU Haixia,HUANG Zufang,HUANG Meiya,ZHENG Liangpu,LIN Ruhui,DU Jian 1.Key Laboratory of Fujian Academy of Integrative Medicine,Fuzhou 350108,China 2.Fujian Key Laboratory of Integrative Medicine on Geriatrics(Fujian University of TCM),Fuzhou350108,China 3.The Key Laboratory of Basics of Integrative Medicine of Fujian Higher Education(Fujian University of Traditional Chinese Medicine),Fuzhou 350108,China;STUDY ON THE EFFECT OF COMPOUND CHINESE MEDICINE JIEDU-XIAOZHENG-YIN ON APOPTOSIS RELATED GENES OF GASTRIC CARCINOMA CELLS BY LSCM[A];[C];2009
5 CHEN Si-wen,WANG Wen-ge,and WANG Shou-chuan.Department of Pediatrics,Xiamen hospital of TCM,Xiamen(361001);Effect of Qingfei Oral Liquid on Protein Expression of Fas and FasL of Human Embryonic Lung Fibroblast Cells Induced by Adenovirus Type 3I,7b[A];[C];2006
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 HU Rong et al(College of Chemistry and Life Science,Neijiang Normal University,Neijiang,Sichuan 641100);Toxic Effects of Hg~(2+) and Cd~(2+) on Embryo Development and Larva Fish of Carassius auratus[J];Journal of Anhui Agricultural Sciences;2010-34
2 Wang Xiang,Fu Chuan,Pan Jie,Cheng Cong(College of Chemical and Environmental Engineering,Chongqing Three Gorges University,Chongqing 404000,China);Study on Leaching Toxicity and Cd Pb Release Characteristic of Manganese Mine Tailing and Slag[J];Environmental Science and Management;2010-07
3 REN Ji-ping,LI De-fa,ZHANG Li-ying (MAFIC,China Agricultural University,Beijing 100094,China);ADVANCES OF THE TOXICOLOGY OF CADMIUM[J];Acta Zoonutrimenta Sinica;2003-01
4 Huang Li(Department of Veterinary Medicine, Gansu Agrisultural University, Lanzhou 730070);Haemological Parameter Changes of the Sheep Experimentaly Toxified with Lead and Cadmium and Detoxified by Selenium[J];JOURNAL OF GANSU AGRICULTURAL UNIVERSITY;1998-04
5 WANG Hong fei (Jinzhong City Environment Monitoring Station,Shanxi Jinzhong\ 030600,China);Study on Cd Pollution in Environment and Its Effects on Cd Exposure People[J];Trace Elements Science;2002-07
6 LIU Wei-cheng, LI Ming-yun(Faculty of Life Science and Bioteehnology, Ningbo University, Ningbo 315211, China);Research Advance of Toxicological Effects and Toxigenictity Mechanism of Cadmium[J];Guangdong Trace Elements Science;2005-12
7 ZHANG Ya-hui,LIU Zheng-tao,WANG Yi-zhe,YAN Zhen-guang,WANG Hong,YANG Ni-yun Key Laboratory of Ecological Effect and Risk Assessment of Chemicals,Ministry of Environmental Protection,Chinese Research Academy of Environmental Sciences,Beijing 100012,China;Joint Toxicity of Cu~(2+) and Cd~(2+) to Early Development of Zebrafish Embryos[J];Research of Environmental Sciences;2010-11
8 JIA Xiuying WANG Meizhen Hangzhou Key Laboratory of Zoology Science and Technology,Hangzhou Normal University,Hangzhou 310036;Study on the reproductive toxicity of subacute cadmium exposure in male Rana nigromaculata[J];Acta Scientiae Circumstantiae;2007-09
9 ZHANG Yu-zeng, CHEN Lan, JU Ying, et al. Department of Occupational and Environmental Health and MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei 430030, China;Levels of Cadmium and Lead and Copper in Blood and Urine Samples from Residents Exposed to the E-waste Recycling Environment[J];Journal of Environment and Health;2007-08
10 AN Hong-min, ZHENG Wei, GAO Yang. The Forth Hospital of Hebei Medical University ,Shijiazhuang, Hebei 050011, China;Research Progress in Cadmium Toxicity[J];Journal of Environment and Health;2007-09
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 DU NAN-SHAN LAI WEI NAN CHUN-RONG JIANG HUAN-WEI (Department of Biology, EaSt China Normal University, Shanghai 200062);THE MORPHOLOGY AND ULTRASTRUCTURE OF THE MATURE EGG OF ERIOCHEIR SINENSIS (CRUSTACEA, DECAPODA)[J];Acta Zoologica Sinica;1995-03
2 DU Nan Shan LAI Wei CHEN Peng Cheng CHENG Yon Xu NAN Chun Rong (Department of Biology,East China Normal University,Shanghai 200062,China);STUDIES ON VITELLOGENESIS OF ERIOCHEIR SINENSIS[J];ACTA ZOOLOGICA SINICA;1999-01
3 YAN Bo, WANG Lan , LI Yong-Quan, LIU Na, WANG QianCollege of Life Science and Technology, Shanxi University, Taiyuan 030006, China;Effects of cadmium on hepatopancreatic antioxidant enzyme activity in a freshwater crab Sinopotamon yangtsekiense[J];Acta Zoologica Sinica;2007-06
4 LI Chang-hong,JIN Shan(College of Life Science and Biotechnology,Key Laboratory of Applied Marine Biotechnology,Ministry of Education,Ningbo University,Ningbo 315211,China);Preliminary Study on Immune Function of the Haemolymph in Crab Portunus trituberculatus[J];Fisheries Science;2008-04
5 XU Hai sheng\+1,\ XU Bu jin\+2(1.College of Animal Science, Zhejiang University, Hangzhou 310029,China;\ \ \ \ \ \ 2.Institute of Nuclear Agricultural Science, Zhejiang University, Hangzhou 310029, China);Progress on the researches of cellular and humoral immunity of crustacean[J];Journal of Dalian Fisheries University;2001-01
6 Wang Qiang; Yao Sumei; Guo Xiuling (Kaifeng Medical College, Kaifeng 475001);Distribution of Cadmium in Main Organs of Acute Cadmiun Poisoned Rats[J];TRACE ELEMENTS SCIENCE;1998-09
7 LIU Wei-cheng, LI Ming-yun(Faculty of Life Science and Bioteehnology, Ningbo University, Ningbo 315211, China);Research Advance of Toxicological Effects and Toxigenictity Mechanism of Cadmium[J];Guangdong Trace Elements Science;2005-12
8 Weng Huanxin (Department of Earth Sciences,Zhejiang University,Hangzhou 310027)B. J. Presley (Department of Oceanography,Texas A&M University,USA);BIOACCUMULATION OF HEAVY METALS IN OYSTER (CRASSOSTREA VIRGINICA)[J];ACTA SCIENTIAE CIRCUMSTANTIAE;1996-01
9 YU Ri an,CHEN Xue min Department of Environmental Health, School of Public Health, Tongji Medical University, Wuhan 430030;Effects of Cadmium on DNA Damage in Rat Liver Cells,in Vivo and in Vitro Studies With Single Cell Gel electrophoresis[J];Journal of Environment and Health;2000-05
10 CHANG Guo-Liang1,WU Xu-Gan1,CHENG Yong-Xu1,WANG Zong-Kai1,LIU Qiang1,YANG Xiao-Zhen1,LU Jian-Feng2(1.Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources,Shanghai Fisheries University,Ministry of Education,Shanghai,200090;2.School of Biotechnology and Food Engineering,Hefei University of Technology,Hefei,230009);EFFECT OF LIPID NUTRITION ON HEPATOSOMATIC INDEX AND BIOCHEMICAL COMPOSITION OF JUVENILE ERIOCHEIR SINENSIS[J];Oceanologia Et Limnologia Sinica;2008-03
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