Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Marine Sciences》 2001-02
Add to Favorite Get Latest Update

PHARMACOKINETICS STUDY OF SULFAMETHAZINE IN PERCH

WANG Qun SUN Xiu tao LIU De yue LIU Qi LI Jian(Yellow Sea Fisheries Research Institute, Qingdao 266071)  
This article first reports Pharmacokinetic of Sulfamethazine in Perch after oral administration by high performance liquid chromatography .The result demonstrates: dates of SMZ concentrations versus time were conformed to one compartment open model after a single oral administration at a dose of 200×10-6, and the primary parameters were shown bellow :Absorption rate constant (K a)was 0.096 h-1 . Time when maxium concentration was obtained(Tmax) was 21.479 h. Maxium concentration(Cmax)was 50.768 μg/ml, Absorption half life(T(1/2)Ka)was 7.250 h, Elimination half life(T(1/2)K)was 38.299 h, Area under serum concentration (AUC) was 4 138.400(mg·h)/L. We can determine the concentrations in four tissues (muscle, blood, liver and kinedy) after 0.5 h for administration and the maxium concentration was determined at 16 h after administration,Average recoveries were 80%-90% in muscle, blood and liver, and the limit of determination was 0.05×10-6.
【Fund】: 农业部科研项目“鱼用药物代谢动力学及药物残留的研究”
【CateGory Index】: S948
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Pei-qi~(1,2),LI Jian~2,WANG Qun~2,LIU Qi~2,GUAN Bin~1(1.Ocean University of China,Qingdao 266003,China;2.Yellow Sea Fishery Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China);The Residues and Elimination of Sulfamethoxazole in Chinese shrimp Fenneropenaeus chinensis[J];Fisheries Science;2005-11
2 GAI Chun-lei,ZHU An-cheng,LI Tian-bao,YE Hai-bin,XU La,WANG Yong-qiang,WANG Shu-jun(Mariculture Institute of Shandong Province/Key Laboratory for Mariculture Disease Treatment of Shandong Province,Qingdao,Shandong 266002,China);Pharmacokinetics of trimethoprim in Scophthatmus maximus[J];Journal of Fujian Agriculture and Forestry University(Natural Science Edition);2009-06
3 GAI Chun-lei,ZHU An-cheng,LI Tian-bao,YE Hai-bin,XU La,WANG Yong-qiangThe Mariculture Research Institute of Shandong Province,Qingdao 266002,China);Pharmacokinetics of Trimethoprim in Japanese Flounder(Paralichthys olivaceus)[J];Fisheries Science;2010-01
4 ZHANG Hong-yu,ZHAO Ming-jun,ZHOU Zhuang(Chinese Academy of Fishery Sciences,Beijing,100141,China);Study Status in Pharmacokinetics of Fishery Medicines in China[J];Progress in Veterinary Medicine;2010-12
5 FANG Xing-Xing LI Jian WANG Qun LIUXiu-Hong (YellowSea Fishriers Research Istitute,Chinese Academy of Fishery Science,Qingdao,266071);RESIDUAL CHARACTERISTICS OF SULFAMETHOXAZOLE AND TRIMETHOPRIM IN Lateolabrax japonicus AT DIFFERENT WATER TEMPERATURE[J];Marine Sciences;2003-09
6 TANG Xue lian 1 WANG Qun 2 LI Jian 2* ( 1Northeast Agricultural University,Harbin 150030) ( 2Yellow Sea Fisheries Research Institute,Qingdao 266071);Studies on pharmacokinetics and residues of Chloramphenicol in perch( Lateolabras janopicus) in vitro[J];Marine Fisheries Research;2003-02
7 LI Jing-yun 1,2 LI Jian 1* WANG Qun 1 ZHAN Wen-bin 2( 1Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071)( 2Fishery College, Ocean University of China, Qingdao 266003);Pharmacokinetics studies on sulphamonomethoxine in Fenneropenaeus chinensis[J];Marine Fisheries Research;2006-04
8 WANG Qun1 LIU Qi1 LI Jian1 LEI Ji-lin1 SUN Xu-wen2(1Key Laboratory of Sustainable Utilization of Marine Fisheries Resources,Ministry of Agriculture Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Scienses,Qingdao 266071)(2Commodity Inspection Bureau of Rongcheng,Weihai 264300);Residue elimination of florfenicol,oxytetracycline and sulfamonomethoxine in Scophthalmus maximus following oral administration[J];Marine Fisheries Research;2008-05
9 SUN Yu-zeng LIU Hui-hui QIN Hua-wei ZHANG Shi-juanXING Hong-yan XU Ying-jiang GAO Ji-qing(Shandong Provincial Marine Fisheries Research Institute,Yantai 264006);Pharmacokinetics of sulfamethoxazole in turbot after oral administration[J];Progress in Fishery Sciences;2009-06
10 TANG Jun~1,ZHENG Zong-lin~(1,2),YANG Xian-le~1,HU Kun~1,YU Wen-juan~1(1.E-institute of Shanghai Municipal Education Commision,Key Laboratory of Aquatic Genetic Resources and Aquaculture Ecology Certificated by the Ministry of Agriculture,Fishery Pathogen Collection of the Ministry of Agriculture,Shanghai Fisheries University,Shanghai 200090,China;2.College of Aquaculture,Southwest University,Rongchang 402460,China);Metabolism and elimination of sulfamethoxazole in tissues of Chinese mitten-handed crab (Eriocheir sinensis)[J];Journal of Shanghai Fisheries University;2006-04
China Proceedings of conference Full-text Database 1 Hits
1 GAN Ju-li JIA Xiao-ping (1.South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Key Lab.of Mariculture,Ecology and Quality Control,Ministry of Agriculture,Key Lab.of Fishery Ecology Environment,Guangdong Province of China,Guangzhou,510300,China);Toxic and residual effect of chemical antibiotics on fish[A];[C];2010
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HUANG Bin,CHANG Hongjun(Dept of Biol Xinyang Normal College,Xinyang 46400,China);The Effect of Different Chemicals on Ichthyophthirius Disease in Goldfish[J];Fisheries Science;2003-02
2 LV Hao~(1,2), ZHOU Bo-wen~1(1. School of Life Science and Technology, Dalian Fisheries University, Dalian f Agriculture, People's Republic of China, Dalian 116023, China);Acute Toxicity of Four Drugs to Juvenile Sea Cucumber(Apostichpus japonicus)[J];Fisheries Science;2005-06
3 ZHANG Pei-qi~(1,2),LI Jian~2,WANG Qun~2,LIU Qi~2,GUAN Bin~1(1.Ocean University of China,Qingdao 266003,China;2.Yellow Sea Fishery Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China);The Residues and Elimination of Sulfamethoxazole in Chinese shrimp Fenneropenaeus chinensis[J];Fisheries Science;2005-11
4 WU Ting1,2,GU Wei1,WANG Wen1(1.Jiangsu Key Laboratory for Bioresources & Biotechnology,College of Life Sciences,Nanjing Normal University,Nanjing 210046,China;2.Baoying Center for Control and Prevention of Aquatic Animal Infectious Diseases in Jiangsu Province,Baoying 225800,China);Medication of the Tremor Disease in Chinese Mitten Crab Eriocheir sinensis[J];Fisheries Science;2008-07
5 YE Ji dan,HAN You wen,LU Tong yan,YANG Yu hui, LIU Hong bai,ZHAO Ji wei (Heilongjiang River Fishery Research Institute,Chinese Academy of Fishery Sciences,Harbin,Heilongjiang 150070,PRC);Toxicity of olaquindox to fish I Growth performances and changes of quantity and conformation of microflora in the intestine of carp Cyprynus carpio fed with feed containing different concentrations of olaquindox[J];Journal of Northeast Agricultural University;2003-02
6 YANG Yu-hui~(1,2), LU Tong-yan~1, ZHAO Ji-wei~1,LIU Hong-bai~1(1.Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; 2.Life Science and Agriculture College, Hainan University, Haikou 570228, Hainan Province, China);A detection method of ciprofloxacin residues in common carp tissues[J];Journal of Dalian Fisheries University;2004-02
7 LI Qiang, LUO Yong-cheng, LI Hua, CHANG Ya-qing (Key Laboratory of Mariculture & Biotechnology, Agriculture Ministry, PRC, Dalian Fisheries Univ., Dalian 116023, China);Acute toxicity of common antibiotics and disinfectants to juvenile sea cucumber (Apostichopus japonicus)[J];Journal of Dalian Fisheries University;2005-02
8 ZHANG Yao-wu1,CHEN Wan-guang1,LI Wen-hui2,GUO Dai-jian1(1.Department of Life Science,Luoyang normal university,Luoyang,Henan 471022;2.Luoyang Fanya Feed Limited Company,Luoyang,Henan 471021);Effect of Chinese Herbal Medicines on Growth and Nonspecific Immunity of Macrobrachium rosenbergii[J];Freshwater Fisheries;2008-06
9 WANG Gao xue 1,BAI Zhan tao 2,ZHANG Xiang qian 2, MA Xing wu 1,LU Ren jun 3 (1.College of Animal Science and Veltevinary Medicine Northwestem Agricultural University, YangLing, Shaanxi 712100;2.Yan An University;3.Experimental Base of Fry, R;Studies on a Fish Drug“Yu XiaKang-Ⅰ” of New Quinolones[J];PROGRESS IN VETERINARY MEDICINE;1999-04
10 Lin Nengfeng Xu Binfu Gong Hui Dong Chuanfu Lin Tianlong (Fish Disease Control center,Fujian Academy of Agricultural Science,Fuzhou 350003);Elementary Research on “White-Liver Disease” Prevention and Cure of Pseudosciaena crocea in Cage Aquaculture[J];Fujian Journal of Animal Husbandry and Veterinary;2001-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIU Qian et al(Fisheries College,Huazhong Agricultural University,Wuhan,Hubei 430070);Changes of Biochemical Characteristics and Organization Structure in Liver of Grass Carp(Ctenopharyngodon idellus) with Hepatobiliary Syndrome[J];Journal of Anhui Agricultural Sciences;2009-14
2 WU De-ling,JIN Chuan-shan,LIU Jin-qi,SHAO Hai-feng(Department of Pharmacy,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China);Quantitative Determination of the Total Flavanone Content in Fructus Alpinia Oxyphylla[J];Journal of Anhui Traditional Chinese Medical College;2005-06
3 LI Yun1,RU Shao-guo2(1 College of Fisheries,Ocean University of China,Qingdao 266003,Shandong,China;2 College of Marine Life Sciences,Ocean University of China,Qingdao 266003,Shandong,China);Effects of monocrotophos on GPT and GOT activities in the goldfish (Carassius auratus) livers and serum[J];Journal of Safety and Environment;2008-05
4 QIAN Yun-Yun TANG Jun ZHENG Zong-Lin YANG Xian-Le(Aquatic Pathogen Collection Center of Ministry of Agriculture,Shanghai Fisheries University,Shanghai 200090,China);Pharmacokinetics of Enrofloxacin in Macrobrachium rosenbergii[J];Chinese Journal of Zoology;2007-05
5 LI Hai-Di YANG Xian-Le HU Kun WANG Xiang-Ling(Aquatic Pathogen Collection Center of Ministry of Agriculture,Shanghai Ocean University,Shanghai 201306,China);Pharmacokinetics and the Elimination Regularity of Difloxacin and its Metabolite Sarafloxacin in Eriocheir sinensis[J];Chinese Journal of Zoology;2009-02
6 WU Qiu-yan,LIANG Wen-zhen (1.Liaoning Developmental Center of Green Food,Shenyang 110036, China; 2.Liaoning College Agricultural Vocational Technology, Gaizhou 115214, China);Process Technologies of Portulaca Oleracea L[J];Storage & Process;2006-02
7 MAO Zhi juan,ZHUO Hua long (Ningbo Fishery Research Institute,Ningbo 315010 China);Studies on the Pathogen of the Bacteria Epidemic against Mud Crab Scylla serrata[J];Fisheries Science;2001-01
8 SUN Hong xiang,TAO Yong jun (College of Animal Science,Zhejiang University,Hangzhou 310029,China);Pharmacodynamic Study on Biebaoning against Disease in Soft shelled Turtle (Trionyx sinensis)[J];Fisheries Science;2001-04
9 XU Wei-hai~(1,3),LIN Li-ming~2, ZHU Xiao-bin~1, WANG Xin-ting~1,HUANG Xin-ping~1 , KANG Xing-lun~1(1.Center of Biotechnology, Institute of Oceanology,Chinese Academy of Science,Qingdao 266071,China;2.Food Laboratory of Qingdao Entry-Exit Inspection and Quaranrine Bureau of P.R.China, Qingdao 266002,China;3.Graduate School, Chinese Academy of Science,Beijing 100039,China);Residues of Enrofloxacin and Its Metabolite in Jifu Tilapia and Penaeus chinensis[J];Fisheries Science;2004-07
10 ZHENG Tian-lun~1,WANG Guo-liang~2,JIN Shan~2(1.Zhejiang Fisheries Technical Extension Center, Hangzhou 310012,China; 2.Department of Oceanology and Fishery, Ningbo University, Ningbo, 315211,China);Administration of Chinese Herb Medicines in Control of Vibriosis in Cage-cultured Large Yellow Croaker[J];Fisheries Science;2005-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Pei-qi~(1,2),LI Jian~2,WANG Qun~2,LIU Qi~2,GUAN Bin~1(1.Ocean University of China,Qingdao 266003,China;2.Yellow Sea Fishery Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China);The Residues and Elimination of Sulfamethoxazole in Chinese shrimp Fenneropenaeus chinensis[J];Fisheries Science;2005-11
2 GUO Hai-yan1,2,CHEN Yuan-kun1,ZHU Lin3,ZHANG Qi-zhong2,4(1.Chongqing Fishery Sciences Research Institute,Chongqing 400020,China;2.Key Laboratory of Aquatic Science,Chongqing College of Life Science,Southwest University,Chongqing 400715,China;3.Tongliang Fisheries Station,Chongqing 402560,China;4.Hydrobiology Institute of Jinan University,Guangzhou 510632,China);The Distribution and Pharmacokinetics of Norfloxacin in Tissues in Grass Carp[J];Fisheries Science;2009-01
3 Zhang Yanqiu, Zhan Yong, Huang Lei;Effects of Saccharicterpenin on Growth Performance and Meat Quality in Colossoma Sp[J];Feed Industry;2005-04
4 LIN Qing-yuan(Fisheries Research Institute of Xiamen,Xiamen 361005,China);Enzyme Linked Immumosorbent Assay (ELISA) for Quantitative Analysis of Furazolidone Metabolite (AOZ) Residues in Aquatic Products[J];Journal of Fujian Fisheries;2008-04
5 Zhang Chunyan,Zhou Xiaozhi,Zhang Wenqin;Determination of L-ascorbic acid-2-phosphate in aquaculture feed by reversed phase high performance liquid chromatography[J];Feed Industry;2009-20
6 QIU Deng-gao1,ZHENG Shu-ming2,ZHANG Hong-yu3,ZHENG Zong-lin2,NIE Li-rong2(1.The Center for Sturgeon on breeding and Technological Engineering,Chinese Academy of Fishery Sciences,Beijing 100070;2.The Fish Breeding and healthy culture Research Center,Southwest University,Chongqing 402460;3.Chinese Academy of Fishery Sciences,Beijing 100141);Pharmacokinetics of gallic acid of Fructus chebulae in Carassius auratus gibelio[J];Freshwater Fisheries;2010-03
7 ZHANG Hong-yu,ZHAO Ming-jun,ZHOU Zhuang(Chinese Academy of Fishery Sciences,Beijing,100141,China);Study Status in Pharmacokinetics of Fishery Medicines in China[J];Progress in Veterinary Medicine;2010-12
8 LIAO Bi-chai,FAN Hai-ping,LIN Li-cong,YU Pei-jian(Institute of Freshwater Fisheries of Fujian Province,Fuzhou,Fujian 350002,China);Pharmacokinetics and residues of neomycin sulfate in hybrid tilapia(Oreochromis aureus×O.niloticus)[J];Journal of Fujian Agriculture and Forestry University(Natural Science Edition);2011-01
9 CAO Li-min~(1,2),~()LI Jian~(1),~()LIU Qi~(1),~()WANG Qun~(1)(1.Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China;(2.College) of Life Science and Technology,Shanghai Fisheries Univerity,Shanghai 200090,China);Studies on pharmacokinetics of norfloxacin in Litopenaeus vannamei fed Artemia enriched with norfloxacin[J];Marine Sciences;2006-05
10 WANG Qun1 LIU Qi1 LI Jian1 LEI Ji-lin1 SUN Xu-wen2(1Key Laboratory of Sustainable Utilization of Marine Fisheries Resources,Ministry of Agriculture Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Scienses,Qingdao 266071)(2Commodity Inspection Bureau of Rongcheng,Weihai 264300);Residue elimination of florfenicol,oxytetracycline and sulfamonomethoxine in Scophthalmus maximus following oral administration[J];Marine Fisheries Research;2008-05
China Proceedings of conference Full-text Database 1 Hits
1 GAN Ju-li JIA Xiao-ping (1.South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Key Lab.of Mariculture,Ecology and Quality Control,Ministry of Agriculture,Key Lab.of Fishery Ecology Environment,Guangdong Province of China,Guangzhou,510300,China);Toxic and residual effect of chemical antibiotics on fish[A];[C];2010
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved