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《CHINESE JOURNAL OF MARINE DRUGS》 1999-02
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AN EXPERIMENTAL STUDY ON THE EFFECTS OF MERETRIX POLYSACCHARIDE ON ANTINEOPLASTIC AND IMMUNORGULATION

Don Changgui;Huang Fang;Huang Luosheng,et al (China Pharmaceutical University Nanjing 210038 )  
The results indicated that Meretrix polysaccharide (was given orally, 100mg/ kg. 200mg/kg ) could remarkably reduce the weight of S_(180) solid carcinoma in mice, prolong the survival period of mice with EAC ascites carcinoma and hepatic carinoma. It had no effect on L_(1210) leukemia. It also showed that Meretrix polysaccharide could significantly improve the Index of thymus and spleen, Increase the number of leukocyte, improve the phagocytic power, increase the production of serum hemolvsin and enhance the SRBC DTH and PC-DTH reac- non in immunodepressed mice induced by cvclophosphamide. It is suggested that Meretrix polysaccharide has effects on antineoplastic a.d immunoregulation.
【CateGory Index】: R285
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