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《CHINESE JOURNAL OF MARINE DRUGS》 1999-02
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THE IMMUNO-STIMULATING ACTIVATIONS OF SQUID INK AND ITS EXTRACTS

Ly Changlong;He Shen;Liu Beixing,et al. (Department of Immunology,China Medical University Shenyang 110001 )  
We investigated the inducing activities of squid ink and its extracts on the secretor levels of interleukine 1 (IL-1 )and tumor nectosis factor α(TNFα)and the killing ability of natural killer (NK)sells to understand further the mechanisms of their anti-tumors. The results showed that both IL-1 and TNF a levels in the animals treated with squid ink and its extracts were significantly higher than those in the control (P0. 01 ). The killing ability of the NK cells from the animals in the test group was also increased remarkably. These findings indicated that squid ink and its extracts might activate the cellular immunity by their stimulating NK cells and macrophages to Inhibit or kill tumor cells Indirectly.
【CateGory Index】: R284
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