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《CHINESE JOURNAL OF MARINE DRUGS》 2000-03
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TO OBSERVE THE EFFECTS OF CHITOSAN ON REDUCE THE PLASMA LIPID CONCEGTRATION

Gu Yun,Wang Luya,Zhang Ying,et al (Medical Institute of Beijing Heart Lung and Blood Vessel,Beijing 100029)  
To observe the effect of Chitosan in patients with hyperlipidemia.31 out-patients with hyperlipidemia were selected and administrated Chitosan 2g·d 1 for one month.The effects of Chitosan to reduce the lipid levels were evaluated,while its influence on liver were observed by abdominal B-type ultrasonography and the measure of serum AST、ALT.Plasma trighyceride level were reduced by 32.6%(P0.05),plasma cholesterol level were reduced by 12.0%(P0.01) and low-density lipoprotein 12.8%(P0.05).Before and after the administration of Chitosan,serum of AST、ALT maintained normal level while no significant changes were found by liver B type ultrasonography.The effects of Chitosan on reduce the plasma lipid levels were definite without damaging liver function.
【CateGory Index】: R285
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