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《Chinese Journal of Marine Drugs》 2004-05
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Studies on the chemical constituents from the mycelia of marine fungus Aspergillus versicolor

ZHANG Hai-long 1,TIAN Li 2,HUA Hui-ming 1,PEI Yue-hu 1 (1. School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016 ,China;2. First Institute of Oceanography,State Oceanic Administration,Qingdao 266003,China)  
Objective To study the chemical constituents from mycelium of marine fungus Aspergillus versicolor.Methods The compounds were separated by column chromatography and their structures were elucidated based on chemical and spectral analysis. Results Seven compounds have been isolated from the acetone and methanol extracts from the mycelia of Aspergillus versicolor. Their structures were determined as sterigmatocystin (I), 6-methoxysterigmatocystin (II), averufin (III), tyrosine (IV), 3-methyl-pyrrolopiperazine-2, 5-dione (V), 3-isopropyl-pyrrolopiperazine-2, 5-dione (VI), carbamide (VII). Conclusion Compounds IV,V and VI were isolated for the first time from this genus of marine fungi.
【Fund】: 国家 8 6 3项目 (2 0 0 1AA6 2 4 0 2 0 )
【CateGory Index】: Q946
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1 Wen Han LIN1*, Hong Zheng FU1, Jun LI1, Peter Proksch2 1National Research Laboratories of Natural and Biomimetic Drugs, Peking University, Beijing 100083 2Institut fuer Pharmazeutwasche Biologie, Heinrich-Heine Universitat, Duesseldorf D-40225;Novel Chromone Derivatives from Marine Fungus Aspergillus versicolor Isolated from the Sponge Xestospongia exigua[J];中国化学快报(英文版);2001-03
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