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《Chinese Journal of Marine Drugs》 2005-01
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Screening of bioactive products in twelve kinds of marine animals from Zhoushan archipelago in Zhejiang province

FAN Qiu-ling, HUANG Cai-guo, MIAO Hui-nan, JIAO Bing-hua, YUAN Qin-sheng(1.State Key laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237,China;2.Department of Biochemistry and Molecular Biology,Department of Basic Medicine,Second Military Medical University,Shanghai 200433,China)  
Antimicrobial model and tumor cytotoxic model were applied to screen bioactive products in twelve kinds of marine animals from Zhoushan archipelago in Zhejiang province. The extracts from seven kinds of marine animals with ethanol showed considerable antimicrobial activity against Staphylococcus aureus, of which Bullacta exarata showed maximal antimicrobial activity. The extracts from Solen grandis Dunker and Bullacta exarata with ethanol and Haliplanella luciae with water showed cytotoxic activity, the IC 50 of which against SMMU-7721 was 89,71,63.2μg·mL -1, respectively.
【CateGory Index】: R284
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