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《Chinese Journal of Marine Drugs》 2010-04
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Immunomodulation of Mytihus edulis Linnaeus polysaccharides in mice

LUAN Jie1,XIN Tian2,CHU ZHi-yong1,WANG Jia-chun1,ZHANG Shu1,SHEN Yue1(1.Naval Medical Research Institute,Shanghai 200433,China;2.Liaoning University of Traditional Chinese Medicine,Dalian 116600,China)  
Objective To investigate the immunomodulation of Mytihus edulis Linnaeus polysaccharides(MEP) in mice.Methods After 30 d medication of MEP at doses of 67,133 and 400 mg·kg-1,the weight of immune organs,carbongranular clearance ability,hemolysin production level,DTH and activity of NK cells were determined.Results MEP could significantly enhance the function of the delayed type hypersensitivity and phagocytosis.The serum hemolysins in mice were significantly increased.But there were no effect on the activities of NK cells.Conclusion MEP can improve immune function in mice.
【Fund】: 上海市科委基金资助(No.054319905)
【CateGory Index】: R285.5
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