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Effects of Polygonum Multiflorum Thumb on Patients with Vascular Dementia

Tan Peizhen,Yang Qidong,Tan Xinglin,et al. (Institute of Neurology,Xiangya Hospital,Central Southern University,Changsha 410008,China)  
Objective To evaluate the effects of Polygonum Multiflorum Thumb on patients with vascular dementia.Methods 40 patients with mild to moderate vascular dementia,scored 10 to 24 on MMSE were enrolled;All patients took Polygonum Multiflorum Thumb for 12 weeks;Efficacy was assessed on basis of the scores of MMSE,Activity of Daily Living Scale(ADL),Blessed-Roth Scale and Clinical Global Impression (CGI),at the baseline and at the end of 12 weeks treatment.Results There was a significant difference between pre-and post-treatment in MMSE,ADL,Blessed-Roth and SI(P0 05).The scores of GI and EI were 2.63±1.17 and 2.33±0.76,respectively at the end of 12-week treatment.Polygonum Multiflorum Thumb had no influence on vital signs and laboratory indexes.Conclusion Polygonum Muitiflorum Thumb might significantly improve the cognition and affection and ability of daily life in patients with VD.
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