Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Medical Forum》 2008-18
Add to Favorite Get Latest Update

Significance of Testing Serum Levels of IL-1β、IL-6 and TNF-α in RA Patients

ZHU Minghui,YANG Yi,LIU Xuhua,et al The Fifth People's Hospital of Zhengzhou City,Zhengzhou 450003,China  
Objective To explore the role of cytokines such as IL-1β、IL-6 and TNF-α in the RA pathogenesis function through the determination RA patient and the normal control group serum levels of the cytokines.Methods Gathering 20 RA patients dividing into two groups and 10 heathy people as normal comparative group,each of them adopt ELISA to test the serum level of IL-1β、IL-6 and TNF-α.Results Comparing MTX+TGP+LEF group and MTX group,the former curing effect is obviously better than the latter one.Before the treatment,the higher level of IL-1β、IL-6 and TNF-α in the serum of RA patients than the normal comparative group on average has obviously statistic significance.After the treatment,copmaring the changing level of IL-1β、IL-6 and TNF-α during the treatment in the two RA patients groups has obviously statistic significance.Conclusion IL-1β、IL-6 and TNF-α play an important part in patients's getting sickness and development.
【CateGory Index】: R593.22;R446.6
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 4 Hits
1 BAI Ganping,FANG Yongfei.Southwest Hospital, the Third Military Medical University,Chongqing 400038,China;Cytokines and Rheumatoid Arthritis[J];Journal of Clinical Internal Medicine;2001-04
2 LAO Zhi Ying, NI Li Qing, ZHANG Zhi Li, ZHOU Jia Ling, CHEN Li Hua, ZHANG Fang, LIU Da Dong, YANG Xiao Ling, ZHU Qi, ZHANG Zha Ming, SHEN Jie (Guanghua Hospital, SHANGHAI 200052, China);Leflunomide in treating rheumatoid arthritis: a double blind study[J];Chinese Journal of New Drugs and Clinical Remedies;2001-02
3 WANG Hua,WEI Wei, YUE Li,WANG Ni ping ,GUI Shuang ying,WU Li,SUN Wu yi,XU Shu yun (Institute of Clinical Pharmacology , Anhui Medical University, Hefei 230032,China);Protective effect of total glucosides of paeony on immunological liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide[J];Chinese Pharmacological Bulletin;2004-08
4 GAO Jun1,DING Zhen-qi2.(1.Fujian TCM University,Fuzhou 350003,China; 2.Department of Orthopaedics,175th Hospital of PLA,Zhangzhou 363000,China);The Progress of the Study About the Roles of Cytokines in the Rheumatoid Arthritis[J];Medical Recapitulate;2006-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 HU Cheng-mu,JIANG Hui,LIU Hong-feng,LI Rong,LI Jun (School of Pharmacy,Anhui Medical University,Hefei 230032);Effects of LJTF on immunological liver injury in mice[J];Anhui Medical and Pharmaceutical Journal;2008-04
2 CHEN Fang-jun1,2,WANG Jia-jia1,LI Jun1(1.Anhui Medical University,Hefei,230032;2.Anqing Medical College,Anqing,246003);Protective effect of polysaccharides from yu-ping-feng powder on immunological liver injury in mice[J];Anhui Medical and Pharmaceutical Journal;2008-04
3 SHAO Fu-rong,WEI Wei,LIU Hao,SUN Wu-yi,LI Xiang(Institute of Clinical Pharmacology of Anhui Medical University, Anhui Hefei 230032,China);Comparison of Protective Effect of Shaoqiduogan Extracted by Different Methods on Immunological Liver Injury in Mice[J];Journal of Anhui Traditional Chinese Medical College;2007-05
4 Han Wucheng People Hospital of Guangyuan City,Sichuang Province(628000);Combination Therapy to Rheumatoid Arthritis[J];Journal of Zhejiang University of Traditional Chinese Medicine;2008-05
5 LI Su-fang (Department of Medicine,The General Hospital of Luoyang Bearing Limited Company,Luoyang 471003,China);Levels and significance of TNF-a in peripheral blood and synovial fluid form patients with rheumatoid arthritis[J];Henan Medical Research;2007-01
6 Zeng Xiangfa,Zhou Zhenxiang,Huang Fang(Hubei College of Traditonal Chinese Medicine,Wuhan,Hubei,430065);The Effect of Bai Hu Shan Huang on TNF a and Liver Tissues of Hepatic Injury-suffering Rats Caused by CCI_4[J];Journal of Hubei College of Traditional Chinese Medicine;2007-04
7 ;Progress in research of the effect of Chinese herbal medicine on liver injury[J];Academic Journal of Chinese PLA Postgraduate Medical School;2009-02
8 SAI Qing(Department of Microbiology and Immunology,Xinxiang Medical School,Xinxiang 453000,China);Concentration of TNF-α in Synovial Fluid and Sera from Children with Rheumatoid Arthritis[J];Journal of Henan University of Science & Technology(Medical Science);2007-01
9 MA hui,ZHENG Hai-ying,YUAN Min-zhe,GAO ao,YU Wen-da(Liaoning University of TCM,Shenyang 110032,Liaoning,China);Clinical Research on Rheumatic Arthritis by the Treatment of Sythesis Intervention[J];Liaoning Journal of Traditional Chinese Medicine;2009-10
10 XIAO Kun~* (Department of Clinical Medicine,Peking Union Medical College,Beijing 100730,China);Application of Total Glucosides of Peony in Autoimmune Diseases[J];Chinese Journal of Allergy and Clinical Immunology;2008-01
China Proceedings of conference Full-text Database 1 Hits
1 Hu Chengmu Jiang Hui Liu Hongfeng Li Rong Li Jun (School of Pharmacy,Anhui Medical University,Hefei 230032);Protective effect of Lonicera japonica total flavone(LJTF)on immunological liver injury in mice[A];[C];2007
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 GAO Ze-bin 1 , MA Yue 1, ZHANG Ping 2, MA En-long 3,HAN Qing 4 (1.Department of clinical laboratory, the Second Affiliated Hospital of Dalian Medical University , Dalian 116027 ,China; 2. Endocrine Section; 3. medical institute of Dalian Univers;Analysis of the effect of transforming growth factor-β on the pathogenesis of rheumatoid arthritis[J];Journal of Dalian Medical University;2002-02
2 LI Yinong ,SHI Guiying. Department of Rheumatology,Nanjing Military Region,Fuzhou General Hospital,Fuzhou 350001,China;Expression of interleukin-18 in peripheral blood mononuclear cells from patients with rheumatoid arthritis[J];Chinese Journal of Rheumatology;2001-02
3 Gao Benbo; Dai Liming; Xu Shuyun(Institute of Natural Drugs 261042);THE SCAVENGING ACTIVITIES OF TGM AND TGP ON FREE RADICALS[J];JOURNAL OF WEIFANG MEDICAL COLLEGE;1996-01
4 LAO Zhi-Ying; NI Li-Qing; ZhANG Zhi-Li; ZHANG Zhi-Li; ZHOU Jia-Ling; CHEN Li-Hua; LIU Da-Dong (Guanghua Hospital, Shanghai 200052);Efficacy and safety of total glucosides of peony and methotrexate in treating rheumatoid arthritis[J];;1995-04
5 LAO Zhi-Ying, CHEN Ji-Hong(Guanghua Hospital, Shanghai 200052);Treatment of rheumatoid arthritis with penicillamine plus methotrexate[J];;1997-06
6 Wei Wei, Liang Junshan Zhou Aaiwu et al (The clinical Pharmacology Institute, Anhui Medical University, Hefei );EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-03
7 DAI Li-Ming, CHEN Xue-Guang, XU Shu-Yun (Dept Of Pharmacology, Anhui Medical University, Hefei, 230032);Protective effects of total glucosides of paeony on experimental hepatitis[J];Chinese Pharmacological Bulletin;1993-06
8 ZHOU Ling Ling 1, WEI Wei, SHEN Yu Xian, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032) 1Dept of Pharmacology,Nanjing University of Traditional Chinese Medicine,Nanjing 210029;The effects of TGP on CJ-S_(131)-induced systemic lupus erythematosus-like model in mice[J];Chinese Pharmacological Bulletin;2002-02
9 GE Zhi-Dong; ZHOU Ai-Wu; WANG Bin et al(Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032 );Immunoregulatory effects of total glucosides of paeony (TGP),paeoniflorin (PF) and TGP removed PF on adjuvant arthritic rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1995-04
10 WANG Bin, CHEN Min Zhu, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);Regulatory mechanism of total glucosides of paeony on tumor necrosis factor production by peritoneal macrophages in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1997-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved