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《Journal of Medical Forum》 2009-24
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Effect of Different Combination on Transaminase in Treatment of Rheumatoid Arthritis

SHI Lipu,HE Ya,ZHU Minghui,et al Department of Rheumatology and Immunology,ZhengzhouPeople’s Hospital,Zhengzhou 450003,China  
Objective To investigate the effect of different combination on transaminase in the treatment of rheumatoid arthritis.Methods Total 40 patients were divided into 2 groups randomly,one is the MTX and LEF group,and the other is the MTX and LEF and TGP group with 20 patients.We measured the hepatic function every 4 weeks for three months.Results We found that the effective power of the MTX and LEF and TGP group was 95%,which is obviously higher than that of MTX and LEF group which the effective power is 90%.Patients of the MTX and LEF group experienced more hepatic injury,which usually affected the ones with risk factors after 4 weeks treatment.Conclusion It is more effective in the treatment of active RA combining TGP than the MTX and LEF group,with less hepatic injury.
【CateGory Index】: R593.22
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