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《Journal of Hubei University of Chinese Medicine》 2009-02
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Experimental Research of Acupunctural Pre-stimulation on Changing the Level of Cerebral Radicals of AD Rats

KE Hong1,SUN Guo-jie2,ZHOU Hua2(1.Master postgraduate in grade 2006,Department of Acupuncture and Traumatology,Hubei University of Chinese Medicine,Wuhan 430061,Hubei Province,China;2.Hubei University of Chinese Medicine,Wuhan 430061,Hubei Province,China)  
Objective To investigate,in the light of radical theory,influences in cerebral contents of malondialdehyde(MDA) and glutathioneperoxdaso(GSH-Px) activity by acupunctural pre-stimulation at"Baihui"(DU 20) and "Shenshu"(BL 23) acupoint in rat models of Alzheimer's Disease.Method Changes of cerebral contents of malondialdehyde(MDA) and glutathioneperoxdaso(GSH-Px) activity were determined by spectrophotometry.Results The acupunctural pre-stimulation decreases MDA content and enhances GSH-Px acitivity in model animals.Conclusion Acupuncture treatment delays brain-aging via attenuating neuronal damage caused by cerebral free radicals due to the enhancement of body antioxidative capability by eliminating free radicals.
【Fund】: 国家自然科学基金 [30772837]
【CateGory Index】: R245
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