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《Journal of Hubei University of Chinese Medicine》 2010-01
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Effects of Gynostemma on Transient Hyperuricemia in Mice

LI Hongqin1,YANG Jingmei1,GAO Shan1,ZHAO Min1,HU Jiying2(1.Grade 2004 student of 7 year programme,Hubei University of Chinese Medicine,Wuhan 430061,Hubei;2.College of Fundamental Medicine,Hubei University of Chinese Medicine,Wuhan 430065,Hubei)  
Objective To observe the effects of gynostemma on transient hyperuricemia in male experimental mice.Methods Sixty male mice were randomized into six groups:A,B,C,D,E,and F,which were respectively fed with physiological saline,allopurinol,nothing,high-dose gynostemma,middle-dose gynostemma,low-dose gynostemma for continuous ten days.Once accomplished,the mice apart from group A's were intraperitoneally injected with 0.63g/kg xanthine,resulting in increasing composition of serum uric acid.Then the values of serum uric acid and the activities of mice's livers XOD were measured.Results Comparison of the serum uric acid level and the activities of mice's livers XOD:The difference was highly significant(P0.01)with coamparison of group C,E and B.Conclusions Gynostemma is a promising Chinese herbal medicine,which has the effects of highly decreasing the serum uric acid level on transient hyperuricemia in mice.
【Fund】: 湖北中医学院大学生创新研究项目(2008J002)
【CateGory Index】: R285.5
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Chinese Journal Full-text Database 4 Hits
1 JIN Shenri, ZHENG Jun, LIU Shaotang Basic Medicine College, Chengdu University of TCM (Chengdu, 610075,China);Preliminary Studies on Animal Models of Hyperuricemic Mice[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1999-01
2 Chen Xin-zhi,Huang Xiao-wei,Ou Xi-yan (Changchun University of Traditional Chinese Medicine,Jilin Changchun 130117,China);Experimental Study of Tongfeng An Capsule on the Level of Uric Acid in Rats with Hyperuricemia[J];Journal of Changchun University of Traditional Chinese Medicine;2007-02
3 Wang Yan-gang1,Lu Fu-er1,Wu Yan-qun21Department of Endocrinology of Integrated Chinese and Western Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technolgoy,Wuhan 266003,Hubei Province,China; 2Department of Endocrinology,Affiliated Hosptial of Medical College,Qingdao University,Qingdao 266003,Shandong Province,China;Interventional effect of compound Chinese herb jiang niaosuan mixture on dosage-dependence of hematuria of rats with hypouricemia[J];Chinese Journal of Clinical Rehabilitation;2006-19
4 SUN Wei-feng,LUO Ping,XU Wei,ZHAN Chun-lie,SHI Yu-ling(Guangzhou General Hospital of PLA Guangzhou Military District,Guangzhou 510010,China);Effects of Xiezhuo Chubi Decoction on Serum Uric Acid Level in Model of Hyperuricemic Mice[J];Chinese Journal of Experimental Traditional Medical Formulae;2006-09
Chinese Journal Full-text Database 10 Hits
1 ZHANG PEI,MIAO ZHI-MIN,LI CHANG-GUI,et al (Department of Endocrinology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China);THE METHOD OF CREATING A MODEL OF CHRONIC HYPERURICEMIA IN RATS[J];Acta Academiae Medicinae Qingdao Universitatis;2010-03
2 SU You-xin,CHEN Wei-hong,ZHENG Liang-pu,et al(Department of Orthopedics and Traumatism,Fujian college of TCM,Fuzhou,Fujian 350003,China);Prevention of Tongfeng Granule for High Purine Material Resulting in Transient Hyperuricemia in Little Mouse[J];Journal of Fujian College of Traditional Chinese Medicine;2004-04
3 ZHANG Shuzhe,WANG Zhong,SHI Xueli,et al.Department of Traditional Chinese Medicine,Third Central Hospital of Baoding,Hebei Province,Baoding 071051;Effect of traditional Chinese medicine combined with enalapril on uric acid levels and cardiac function in patients with in chronic heart failure[J];Hebei Journal of Traditional Chinese Medicine;2011-09
4 ZHAO Hui-juan,LI Ning,LIU Ping.College of Health Management,Binzhou Medical University,Yantai,Shandong 264003,China;Effect of Deferiprone on Serum Protein and Liver Zymogram of Aluminum-induced Mice[J];Journal of Environment and Health;2011-06
5 Liu Shao-yan, Miao Ming-san Henan College of Traditional Chinese Medicine,Zhengzhou,Henan,China 450008;Overview on Experimental Animal Model of Gout and Therapeutic Characteristics of Gout with Traditional Chinese Medicine[J];China Journal of Chinese Medicine;2011-01
6 SHI Ping(Department of Pharmacology,Hubei College of Chinese Medicine,Jingzhou 434000,China);Influence on the Subpopulations of T Lymphocytes in Mice Administrated FHZ[J];Journal of Yangtze University(Natural Science Edition)Medicine V;2008-03
7 CAO Yang,WANG Ming-yan(Department of Laboratory,Daxian County People′s Hospital,Daxian,Sichaun 635000,China);Clinical study on screening detection of uric acid and cystatin C in terberculosis patients[J];Laboratory Medicine and Clinic;2012-03
8 YANG Hong-lian,ZHANG Bing,LIU Xiao-qing,LIN Zhi-jian(Traditional Chinese Medicine College of Beijing Traditional Chinese Medical University,Beijing 100029,China);Study of the Hyperuricemia Model of Female Quail[J];Liaoning Journal of Traditional Chinese Medicine;2009-01
9 ZHAO Hui-juan1,LI Ning1,LIU Ping2(1.College of Health Management,Binzhou Medical University,Yantai 264003,China;2.School of Public Health,Shandong University,Jinan 250012,China);Effect of Deferiprone on Activities of Kidney ATPase and Xanthine Oxidase of Aluminuminduced Mice[J];Food and Drug;2011-11
10 HE Li qun, NIE Yong hong, ZHOU Shi Ling (Shu Guang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China);A New Rat Model of Uric Acid Nephropathy[J];Shanghai Laboratory Animal Science;2001-01
Chinese Journal Full-text Database 10 Hits
1 MIN Yong et al (The Chemistry Department of Honghe University,Mengzi,Yunnan 661100);Study on Chemical Constituents of Punica Granatum[J];Journal of Anhui Agricultural Sciences;2006-12
2 LIAN Lian et al(Biological Medicine and Chemical Engineering Institute,Liaoning Institute of Science and Technology,Benxi,Liaoning 117004);Effects of CORTEX PHELLODENDRI and Its Processed Products on Anti-gout[J];Journal of Anhui Agricultural Sciences;2011-15
3 CHENG Fang1,DAI Min1,2,HU Cui-yun1,XUAN Zi-hua1,2(1.School of Pharmacy,Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China;2.Anhui Key Laboratory for Modern Materia Medica,Anhui Hefei 230031,China);Effects of Tongfeng Kang Ethanol Extracts on Metabolism of Uric Acid and Activities of Xanthine Oxidase in Rats with Yeast Extracts Induced Hyperuricemia[J];Journal of Anhui Traditional Chinese Medical College;2011-04
4 HUANG Hai,GAO Zhan-xiang,WANG Hong-mei,et al(College of TCM,FUTCM,Fuzhou,Fujian 350108,China);Regulating Effect of Modified Yinchen Wuling Powder on Xanthine Oxidase Activity in Rats with Hyperuricemia[J];Journal of Fujian University of Traditional Chinese Medicine;2010-04
5 YU Jiang-yi1,XIONG Ning-ning2,LIU Fang2,ZOU Jian-dong2,HUANG Li-ji1,YE Li-fang1,LUO Mei1(1.Department of Eodocrinology;2.Department of Clinical Pharmacology,Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China);Clinical trial of cortex fraxini total coumarin in treating primary hyperuricaemia[J];The Chinese Journal of Clinical Pharmacology;2008-01
6 Sun Xiaobo Dai Zhuqing Li Yi Xie Huan. Chengdu University of TCM Sichuan(Chengdu Sichuan 611730,China);The preliminary study on sangdang to treat hyperuricaemia[J];Journal of Sichuan of Traditional Chinese Medicine;2006-11
7 SHI Le1,XU Li2,TAN Qiu Wei2,YIN Lian3(1.Department of Pharmacology,2.Department of Pharmaceutical Administration Drug Administration,3.Chemistry Department of Chinese Traditional Medicine.Nanjing University of Traditional Chinese Medicine,Nanjing 210046,China);Research of Effective Fractions for Gout in Modified "Si miao Powder"[J];Laboratory Animal and Comparative Medicine;2007-04
8 WANG Yi-xing1 GAO Jian-dong1,2 ZHENG Ping-dong1 HE Li-qun 1,2,3 1.Department of Nephrology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;Key Laborary of Liver and Kindey Diseases,Ministry of Education 2.Institute of Kidney Disease of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine 3.E-institutes of Internal Traditional Chinese Medicine,Shanghai;Effects of "Shizhi Formula" on Uric Acid Metabolism in Rats with Hyperuricemia and Its Mechanism[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2011-04
9 ZHAO Heng-li(Shandong Yantai Municipal Hospital of Traditional Chinese Medicine,Yantai Shandong 26400);Experimental Study on the Mechanism of Hyperuricemia Treated with Erqing Jiangsuan Liquid[J];World Journal of Integrated Traditional and Western Medicine;2011-08
10 YAO Fang-fang1,ZHANG Rui1,FU Rui-juan1,HE Wei2,*(1.College of Public Health,Zhengzhou University,Zhengzhou 450001,China; 2.Henan Academy of Medical and Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China);Effects of Quercetin and Apigenin on Serum Uric Acid and Antioxidant Capacity in Hyperuricemic Rats[J];Food Science;2011-05
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 HOU Bo,HAN Zhi-wu,CAO Yu,CAI Shang-lang(The Affiliated Hospital of Qingdao University Medical College,Qingdao266003,P.R.China);The effects and safety of burdock tea on patients with simple hyperlipemia[J];Shandong Medical Journal;2013-14
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Liu Xiao 1, Li Duan 1,Iyou Kou 2, Minoru Satou 2,Hideo Ueda 2 ( 1 Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200032, China; 2Qipower, Inc. Tokyo,Japan );Effects of Qi salt on the formation or excretion of uric acid[J];Chinese Journal of Clinical Pharmacy;2003-06
2 Wei Feng Sun, Wei Xu, Fu Qing Yao, Hao WangWei Feng Sun,Wei Xu,Fu Qing Yao,Hao Wang,Department of Traditional Chinese Medicine,General Hospital of Guangzhou Command, Guangzhou 510010,Guangdong Province,China;Effect of Xiezhuo chubi decoction in decreasing serum uric acid in gout patients[J];Chinese Journal of Clinical Rehabilitation;2003-21
3 Hu An-ming,Bi Zhi-ming, Li Ping Department of Pharmacognosy, China Pharmaceutical University (Nanjing 210038);Studies on the Chemical Constituents of Achyranthes bidentata[J];Jiangsu Pharmaceutical and Clinical Research;2004-03
4 YU Zhi Feng, YANG Cheng, QIU Xi, CHEN Yan, KONG Ling Dong *, WANG Ming Shi School of Life Sciences, Nanjing University, Nanjing 210093, China;Effects of Daphnin on Serum Uric Acid Level in in vivo Model of Hyperuricemic Mice[J];Journal of China Pharmaceutical University;2002-02
5 WANG Hai-dong, GE Fei, GUO Yu-song, KONG Ling-dong(State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences,Nanjing University, Nanjing 210093,Jiangsu, China; Brain Hospital Affiliated to Nanjing Medical University, Nanjing 210029,Jiangsu, China);Effects Of Aqueous Extract in Herba of Lysimachia christinae on Hyperuricemia in Mice[J];China Journal of Chinese Materia Medica;2002-12
6 TANG Can,YANG Kui (Dept.of pharmacology,Chendu University of TCM,Chendu 610075);A Preliminary Study on the Establishment of Animal Model with Hyperuricemia[J];Traditional Chinese Drug Research & Clinical Pharmacology;2000-05
7 NING Lian 1 ,JIN Ruomin 1 ,WU Yaoping 1 ,ZHANG Haigui 1 ,QI Haihong 1 ,ZHANG Ming 2 ,LI Bin 2 (1.Shanghai uni-versity of TCM,Shanghai 200032;2.Yueyang Hospital of Traditional Chinese Medicine Integrated with Western Medicine,Shanghai 200437);Experimental Study of Gout Granule f or Gout[J];Traditional Chinese Drug Research & Clinical Pharmacology;2003-01
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